Osteoarthrosis: An old disease, novel approaches

Osteoarthrosis (OA) is one of the most common diseases in the elderly; nonetheless, its treatment calls for further investigation. Present views are changing on the pathophysiology of OA, the role of the subchondral bone (SB), and an interaction between SB and articular cartilage in the natural hist...

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Main Author: Aleksandr Ivanovich Dubikov
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2013-06-01
Series:Современная ревматология
Subjects:
Online Access:https://mrj.ima-press.net/mrj/article/view/486
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author Aleksandr Ivanovich Dubikov
author_facet Aleksandr Ivanovich Dubikov
author_sort Aleksandr Ivanovich Dubikov
collection DOAJ
description Osteoarthrosis (OA) is one of the most common diseases in the elderly; nonetheless, its treatment calls for further investigation. Present views are changing on the pathophysiology of OA, the role of the subchondral bone (SB), and an interaction between SB and articular cartilage in the natural history of the disease. Recent data point to novel therapeutic strategies, one of which is to use strontium ranelate in order to delay the progression of chondrolysis in knee and hip OA.
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institution Kabale University
issn 1996-7012
2310-158X
language Russian
publishDate 2013-06-01
publisher IMA-PRESS LLC
record_format Article
series Современная ревматология
spelling doaj-art-19967980f5404f55a8fedcfe8ba7a7d02025-08-20T03:59:57ZrusIMA-PRESS LLCСовременная ревматология1996-70122310-158X2013-06-0172828610.14412/1996-7012-2013-23881791Osteoarthrosis: An old disease, novel approachesAleksandr Ivanovich DubikovOsteoarthrosis (OA) is one of the most common diseases in the elderly; nonetheless, its treatment calls for further investigation. Present views are changing on the pathophysiology of OA, the role of the subchondral bone (SB), and an interaction between SB and articular cartilage in the natural history of the disease. Recent data point to novel therapeutic strategies, one of which is to use strontium ranelate in order to delay the progression of chondrolysis in knee and hip OA.https://mrj.ima-press.net/mrj/article/view/486opg-rank-ranklosteoarthrosissubchondral bonearticular cartilageopg-rank-ranklstructure-modifying activitystrontium ranelate
spellingShingle Aleksandr Ivanovich Dubikov
Osteoarthrosis: An old disease, novel approaches
Современная ревматология
opg-rank-rankl
osteoarthrosis
subchondral bone
articular cartilage
opg-rank-rankl
structure-modifying activity
strontium ranelate
title Osteoarthrosis: An old disease, novel approaches
title_full Osteoarthrosis: An old disease, novel approaches
title_fullStr Osteoarthrosis: An old disease, novel approaches
title_full_unstemmed Osteoarthrosis: An old disease, novel approaches
title_short Osteoarthrosis: An old disease, novel approaches
title_sort osteoarthrosis an old disease novel approaches
topic opg-rank-rankl
osteoarthrosis
subchondral bone
articular cartilage
opg-rank-rankl
structure-modifying activity
strontium ranelate
url https://mrj.ima-press.net/mrj/article/view/486
work_keys_str_mv AT aleksandrivanovichdubikov osteoarthrosisanolddiseasenovelapproaches