Ischemic Stroke and Its Risk Factors in a Registry-Based Large Cross-Sectional Diabetic Cohort in a Country Facing a Diabetes Epidemic
The main aim of this study is to determine the prevalence and risk factors of ischemic stroke among diabetic patients registered in the Saudi National Diabetes Registry (SNDR) database. A cross-sectional sample of 62,681 diabetic patients aged ≥25 years was used to calculate ischemic stroke prevalen...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Journal of Diabetes Research |
| Online Access: | http://dx.doi.org/10.1155/2016/4132589 |
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| author | Khalid Al-Rubeaan Fawaz Al-Hussain Amira M. Youssef Shazia N. Subhani Ahmad H. Al-Sharqawi Heba M. Ibrahim |
| author_facet | Khalid Al-Rubeaan Fawaz Al-Hussain Amira M. Youssef Shazia N. Subhani Ahmad H. Al-Sharqawi Heba M. Ibrahim |
| author_sort | Khalid Al-Rubeaan |
| collection | DOAJ |
| description | The main aim of this study is to determine the prevalence and risk factors of ischemic stroke among diabetic patients registered in the Saudi National Diabetes Registry (SNDR) database. A cross-sectional sample of 62,681 diabetic patients aged ≥25 years was used to calculate ischemic stroke prevalence and its risk factors. Univariate and multivariate logistic regression analyses were used to assess the roles of different risk factors. The prevalence of ischemic stroke was 4.42% and was higher in the older age group with longer diabetes duration. Poor glycemic control and the presence of chronic diabetes complications were associated with a high risk of ischemic stroke. History of smoking and type 2 diabetes were more frequent among stroke patients. Obesity significantly decreased the risk for ischemic stroke. Regression analysis for ischemic stroke risk factors proved that age ≥45 years, male gender, hypertension, coronary artery disease (CAD), diabetes duration ≥10 years, insulin use, and hyperlipidemia were significant independent risk factors for ischemic stroke. We conclude that ischemic stroke is prevalent among diabetic individuals, particularly among those with type 2 diabetes. Good glycemic, hypertension, and hyperlipidemia control, in addition to smoking cessation, are the cornerstones to achieve a significant reduction in ischemic stroke risk. |
| format | Article |
| id | doaj-art-199515d63cfb4a4d96b4e909441ee036 |
| institution | Kabale University |
| issn | 2314-6745 2314-6753 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Diabetes Research |
| spelling | doaj-art-199515d63cfb4a4d96b4e909441ee0362025-08-20T03:55:45ZengWileyJournal of Diabetes Research2314-67452314-67532016-01-01201610.1155/2016/41325894132589Ischemic Stroke and Its Risk Factors in a Registry-Based Large Cross-Sectional Diabetic Cohort in a Country Facing a Diabetes EpidemicKhalid Al-Rubeaan0Fawaz Al-Hussain1Amira M. Youssef2Shazia N. Subhani3Ahmad H. Al-Sharqawi4Heba M. Ibrahim5University Diabetes Center, College of Medicine, King Saud University, P.O. Box 18397, Riyadh 11415, Saudi ArabiaDepartment of Medicine, College of Medicine, King Saud University, P.O. Box 2925, Riyadh 11461, Saudi ArabiaRegistry Department, University Diabetes Center, King Saud University, P.O. Box 245, Riyadh 11411, Saudi ArabiaDepartment of Biostatistics, Epidemiology and Scientific Computing, King Faisal Specialist Hospital and Research Center, P.O. Box 3345, Riyadh 11211, Saudi ArabiaBiostatistics Department, University Diabetes Center, King Saud University, P.O. Box 245, Riyadh 11411, Saudi ArabiaRegistry Department, University Diabetes Center, King Saud University, P.O. Box 245, Riyadh 11411, Saudi ArabiaThe main aim of this study is to determine the prevalence and risk factors of ischemic stroke among diabetic patients registered in the Saudi National Diabetes Registry (SNDR) database. A cross-sectional sample of 62,681 diabetic patients aged ≥25 years was used to calculate ischemic stroke prevalence and its risk factors. Univariate and multivariate logistic regression analyses were used to assess the roles of different risk factors. The prevalence of ischemic stroke was 4.42% and was higher in the older age group with longer diabetes duration. Poor glycemic control and the presence of chronic diabetes complications were associated with a high risk of ischemic stroke. History of smoking and type 2 diabetes were more frequent among stroke patients. Obesity significantly decreased the risk for ischemic stroke. Regression analysis for ischemic stroke risk factors proved that age ≥45 years, male gender, hypertension, coronary artery disease (CAD), diabetes duration ≥10 years, insulin use, and hyperlipidemia were significant independent risk factors for ischemic stroke. We conclude that ischemic stroke is prevalent among diabetic individuals, particularly among those with type 2 diabetes. Good glycemic, hypertension, and hyperlipidemia control, in addition to smoking cessation, are the cornerstones to achieve a significant reduction in ischemic stroke risk.http://dx.doi.org/10.1155/2016/4132589 |
| spellingShingle | Khalid Al-Rubeaan Fawaz Al-Hussain Amira M. Youssef Shazia N. Subhani Ahmad H. Al-Sharqawi Heba M. Ibrahim Ischemic Stroke and Its Risk Factors in a Registry-Based Large Cross-Sectional Diabetic Cohort in a Country Facing a Diabetes Epidemic Journal of Diabetes Research |
| title | Ischemic Stroke and Its Risk Factors in a Registry-Based Large Cross-Sectional Diabetic Cohort in a Country Facing a Diabetes Epidemic |
| title_full | Ischemic Stroke and Its Risk Factors in a Registry-Based Large Cross-Sectional Diabetic Cohort in a Country Facing a Diabetes Epidemic |
| title_fullStr | Ischemic Stroke and Its Risk Factors in a Registry-Based Large Cross-Sectional Diabetic Cohort in a Country Facing a Diabetes Epidemic |
| title_full_unstemmed | Ischemic Stroke and Its Risk Factors in a Registry-Based Large Cross-Sectional Diabetic Cohort in a Country Facing a Diabetes Epidemic |
| title_short | Ischemic Stroke and Its Risk Factors in a Registry-Based Large Cross-Sectional Diabetic Cohort in a Country Facing a Diabetes Epidemic |
| title_sort | ischemic stroke and its risk factors in a registry based large cross sectional diabetic cohort in a country facing a diabetes epidemic |
| url | http://dx.doi.org/10.1155/2016/4132589 |
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