Multigenetic pharmacogenomics–guided treatment shows greater improvements on motor symptoms compared to usual therapy in Parkinson’s disease: a small real-word prospective cohort study

Multigenetic pharmacogenomics–guided treatment shows greater improvements on motor symptoms compared to usual therapy in Parkinson’s disease: a small real-word prospective cohort study

BackgroundDopamine replacement therapy is a cornerstone of Parkinson’s disease treatment. In clinical practice, there is considerable variability in patients’ responses, tolerability, and safety regarding anti-parkinsonian medications, which is largely influenced by genetic polymorphisms in pharmaco...

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Bibliographic Details
Main Authors: Yifan Li, Mao Li, Miao Wang, Jiarui Yao, Fengzhu Li, Siyu Chen, Xi Yin, Zhongbao Gao
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
Subjects:
Parkinson’s disease
pharmacogenomics
single nucleotide polymorphisms
drug efficacy
personalized medicine
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1502379/full
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