The F204S mutation in adrenodoxin oxidoreductase drives salinomycin resistance in Eimeria tenella

The F204S mutation in adrenodoxin oxidoreductase drives salinomycin resistance in Eimeria tenella

Abstract Salinomycin is a polyether ionophore widely used for the treatment of coccidiosis in poultry. However, the emergence of coccidia strains resistant to salinomycin presents challenges for control efforts, and the mechanisms underlying this resistance in Eimeria remain inadequately understood....

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Main Authors: Pei Sun, Chaoyue Wang, Fujie Xie, Linlin Chen, Yuanyuan Zhang, Xinming Tang, Dandan Hu, Yang Gao, Ning Zhang, Zhenkai Hao, Yonglan Yu, Jingxia Suo, Xun Suo, Xianyong Liu
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Veterinary Research
Subjects:
Eimeria tenella
salinomycin
drug resistance
point mutation
Online Access:https://doi.org/10.1186/s13567-024-01431-6
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