Restless Legs Syndrome: A Comprehensive Review of Current Treatment Methods and the Disease's Impact on Quality of Life
Introduction and Purpose of Research: Restless Leg Syndrome (RLS) or Willis-Ekbom disease, is a common neurological disorder significantly impacting one’s sleep and quality of life. It often coexists with various health issues, including diabetes and cardiovascular diseases. Aim of study: The prim...
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| Format: | Article |
| Language: | English |
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Nicolaus Copernicus University in Toruń
2025-01-01
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| Series: | Quality in Sport |
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| Online Access: | https://apcz.umk.pl/QS/article/view/57723 |
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| author | Natalie Papachristoforou Natalia Tekiela Daria Michałka Zuzanna Gałuszka Monika Makar Tomasz Bartuś Emilia Bąk Justyna Głowacka Aleksandra Kocjan Radosław Chmiel |
| author_facet | Natalie Papachristoforou Natalia Tekiela Daria Michałka Zuzanna Gałuszka Monika Makar Tomasz Bartuś Emilia Bąk Justyna Głowacka Aleksandra Kocjan Radosław Chmiel |
| author_sort | Natalie Papachristoforou |
| collection | DOAJ |
| description | Introduction and Purpose of Research: Restless Leg Syndrome (RLS) or Willis-Ekbom disease, is a common neurological disorder significantly impacting one’s sleep and quality of life. It often coexists with various health issues, including diabetes and cardiovascular diseases.
Aim of study: The primary purpose of this research is to explore diverse therapeutic options for RLS which are tailored to individual patient needs. In order to understand the complex pathophysiology of the discussed disease, recent advancements are taken into account.
Material and Methods of Research: The review is grounded in findings from 36 recent studies sourced through a systematic search of open-access databases, including PubMed and Google Scholar, focusing on literature published between 2004 and 2024.
Results: Adequate and effective management of RLS include non-pharmacological interventions, such as physical activity, acupuncture, yoga and near-infrared light therapy, which can complement pharmacotherapy or prevail as the primary treatment form. Iron therapy emerges as vital for many patients. The correlation between iron metabolism and RLS symptoms requires further analysis and research. Pharmacological strategies involve dopaminergic medications, low-potency opioids, and benzodiazepines, with a target on minimizing side effects and dependency.
Conclusion: RLS affects approximately 5-10% of the population, severely disrupting sleep and daily functioning. The condition constrains individualized management, integrating non-pharmacological forms of treatment with pharmacological therapies to improve patient outcomes and reduce dependence on medication.
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| format | Article |
| id | doaj-art-1970aaab1fed4a8b9312e51f601c33e8 |
| institution | Kabale University |
| issn | 2450-3118 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nicolaus Copernicus University in Toruń |
| record_format | Article |
| series | Quality in Sport |
| spelling | doaj-art-1970aaab1fed4a8b9312e51f601c33e82025-01-28T08:25:04ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182025-01-013710.12775/QS.2024.37.57723Restless Legs Syndrome: A Comprehensive Review of Current Treatment Methods and the Disease's Impact on Quality of LifeNatalie Papachristoforou0https://orcid.org/0009-0006-8417-3794Natalia Tekiela1https://orcid.org/0009-0000-5208-251XDaria Michałka2https://orcid.org/0009-0009-6812-6543Zuzanna Gałuszka3https://orcid.org/0009-0009-1729-2146Monika Makar4https://orcid.org/0009-0009-8023-6964Tomasz Bartuś 5https://orcid.org/0009-0000-3980-3191Emilia Bąk6https://orcid.org/0000-0002-6407-4063Justyna Głowacka 7https://orcid.org/0009-0009-8289-8822Aleksandra Kocjan8https://orcid.org/0009-0001-5740-6867Radosław Chmiel9https://orcid.org/0009-0002-2726-6207SP ZOZ MSWiA Hospital in Kraków, Kronikarza Galla 25 street, 30-053 KrakówSP ZOZ MSWiA Hospital in Kraków, Kronikarza Galla 25 street, 30-053 KrakówNZOZ „Centrum Zdrowia i Profilaktyki Dąbie” sp. z o. o., Widok 31 street, 31-567 KrakówSPZOZ Hospital in Myślenice, Szpitalna 2 street, 32-400 MyśleniceNiepołomickie Centrum Profilaktyczno- Lecznicze, Stefana Batorego 41C street, 32-005 NiepołomiceAndrzej Frycz Modrzewski University in Kraków, Gustawa Herlinga-Grudzińskiego 1 street, 30-705 KrakówSP ZOZ MSWiA Hospital in Kraków, Kronikarza Galla 25 street, 30-053 KrakówGabriel Narutowicz Municipal Hospital in Kraków, Prądnicka 35 street, 31-202 KrakówLudwik Rydygier Specialist Hospital, Osiedle Złotej Jesieni 1 street, 31-820 KrakówSP ZOZ MSWiA Hospital in Kraków, Kronikarza Galla 25 street, 30-053 KrakówIntroduction and Purpose of Research: Restless Leg Syndrome (RLS) or Willis-Ekbom disease, is a common neurological disorder significantly impacting one’s sleep and quality of life. It often coexists with various health issues, including diabetes and cardiovascular diseases. Aim of study: The primary purpose of this research is to explore diverse therapeutic options for RLS which are tailored to individual patient needs. In order to understand the complex pathophysiology of the discussed disease, recent advancements are taken into account. Material and Methods of Research: The review is grounded in findings from 36 recent studies sourced through a systematic search of open-access databases, including PubMed and Google Scholar, focusing on literature published between 2004 and 2024. Results: Adequate and effective management of RLS include non-pharmacological interventions, such as physical activity, acupuncture, yoga and near-infrared light therapy, which can complement pharmacotherapy or prevail as the primary treatment form. Iron therapy emerges as vital for many patients. The correlation between iron metabolism and RLS symptoms requires further analysis and research. Pharmacological strategies involve dopaminergic medications, low-potency opioids, and benzodiazepines, with a target on minimizing side effects and dependency. Conclusion: RLS affects approximately 5-10% of the population, severely disrupting sleep and daily functioning. The condition constrains individualized management, integrating non-pharmacological forms of treatment with pharmacological therapies to improve patient outcomes and reduce dependence on medication. https://apcz.umk.pl/QS/article/view/57723Restless leg syndromeWillis-Ekbom diseasesensorimotor disorderneurotransmitter dysfunction |
| spellingShingle | Natalie Papachristoforou Natalia Tekiela Daria Michałka Zuzanna Gałuszka Monika Makar Tomasz Bartuś Emilia Bąk Justyna Głowacka Aleksandra Kocjan Radosław Chmiel Restless Legs Syndrome: A Comprehensive Review of Current Treatment Methods and the Disease's Impact on Quality of Life Quality in Sport Restless leg syndrome Willis-Ekbom disease sensorimotor disorder neurotransmitter dysfunction |
| title | Restless Legs Syndrome: A Comprehensive Review of Current Treatment Methods and the Disease's Impact on Quality of Life |
| title_full | Restless Legs Syndrome: A Comprehensive Review of Current Treatment Methods and the Disease's Impact on Quality of Life |
| title_fullStr | Restless Legs Syndrome: A Comprehensive Review of Current Treatment Methods and the Disease's Impact on Quality of Life |
| title_full_unstemmed | Restless Legs Syndrome: A Comprehensive Review of Current Treatment Methods and the Disease's Impact on Quality of Life |
| title_short | Restless Legs Syndrome: A Comprehensive Review of Current Treatment Methods and the Disease's Impact on Quality of Life |
| title_sort | restless legs syndrome a comprehensive review of current treatment methods and the disease s impact on quality of life |
| topic | Restless leg syndrome Willis-Ekbom disease sensorimotor disorder neurotransmitter dysfunction |
| url | https://apcz.umk.pl/QS/article/view/57723 |
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