Inhibition of mutagenic activation of orthoaminoazotoluene increases its carcinogenicity for mouse liver
Various mutationally impaired genes are often found in malignant tumors of animals and humans. At the same time, a large number of carcinogens demonstrate positive activity in different in vitro tests for mutagenicity. These findings are indicative of a geno- toxic mechanism of carcinogen action. It...
Saved in:
Main Authors: | V. I. Kaledin, L. P. Ovchinnikova, S. I. Ilnitskaya, T. S. Morozkova, N. A. Popova |
---|---|
Format: | Article |
Language: | English |
Published: |
Siberian Branch of the Russian Academy of Sciences, Federal Research Center Institute of Cytology and Genetics, The Vavilov Society of Geneticists and Breeders
2016-12-01
|
Series: | Вавиловский журнал генетики и селекции |
Subjects: | |
Online Access: | https://vavilov.elpub.ru/jour/article/view/819 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Induction of tyrosine aminotransferase in mice is inhibited by activated metabolites of ortho- aminoazotoluene
by: V. I. Kaledin, et al.
Published: (2015-07-01) -
Studies on mutagenic effect of phosphemide in barley
by: N. V. Tetyannikov, et al.
Published: (2022-12-01) -
Correlation of susceptibility to ortho-aminoazotolueneinduced hepatocarcinogenesis with Car and Ahr signaling pathway activation in mice
by: N. V. Baginskaya, et al.
Published: (2015-12-01) -
A simple model of carcinogenic mutations with time delay and diffusion
by: Monika Joanna Piotrowska, et al.
Published: (2013-03-01) -
Carcinogenic and anticancer activities of microbiota-derived secondary bile acids
by: Mobina Kouhzad, et al.
Published: (2025-01-01)