A rare case of upper gastrointestinal hemorrhage due to tuberculous lymphadenitis fistulized in the duodenum

Abstract Introduction Abdominal tuberculosis is less prevalent than pulmonary tuberculosis. Tuberculous lymphadenitis accounts for fewer than 5% of abdominal cases. An unusual complication is the fistulization of a tuberculous lymph node into the digestive tract, with an even rarer association with...

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Main Authors: Souhaib Atri, Mahdi Hammami, Anis Belhadj, Faouzi Chebbi, Youssef Chaker, Montassar Kacem
Format: Article
Language:English
Published: BMC 2025-04-01
Series:International Journal of Emergency Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12245-025-00883-7
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author Souhaib Atri
Mahdi Hammami
Anis Belhadj
Faouzi Chebbi
Youssef Chaker
Montassar Kacem
author_facet Souhaib Atri
Mahdi Hammami
Anis Belhadj
Faouzi Chebbi
Youssef Chaker
Montassar Kacem
author_sort Souhaib Atri
collection DOAJ
description Abstract Introduction Abdominal tuberculosis is less prevalent than pulmonary tuberculosis. Tuberculous lymphadenitis accounts for fewer than 5% of abdominal cases. An unusual complication is the fistulization of a tuberculous lymph node into the digestive tract, with an even rarer association with upper gastrointestinal bleeding. Case Report A 63-year-old male with a history of rectal adenocarcinoma surgery presented with severe gastrointestinal bleeding that required multiple transfusions. Endoscopic attempts failed to locate the bleeding source, but CT angiogram revealed a hemorrhagic necrotic mesenteric lymph node with a fistula to the second part of the duodenum. The patient underwent surgery, which involved resecting the lymph nodes and disconnecting the fistula. Histopathological findings confirmed tuberculous mesenteric lymphadenitis, and the patient was subsequently started on HRZE therapy. Six months postoperatively, there was no recurrence of bleeding. Discussion Gastroduodenal tuberculosis is infrequent due to factors such as the high acidity of the gastric environment and limited lymphoid tissue. Symptoms may mimic other abdominal conditions, making diagnosis challenging. Common complications include gastric outlet obstruction and perforation, while gastrointestinal bleeding is rare. This case of hemorrhagic tuberculous lymphadenitis with fistulization highlights the need for a high index of suspicion and the role of imaging in diagnosing uncommon bleeding sources. While anti-tuberculosis therapy remains the primary treatment, surgery is warranted in cases involving refractory bleeding or fistulization. Conclusion This case emphasizes the importance of a multidisciplinary approach to abdominal tuberculosis with atypical presentations. Awareness of rare complications is essential for prompt diagnosis and management.
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spelling doaj-art-1965bfbf3ceb45d8b749d40eb69033092025-08-20T02:19:57ZengBMCInternational Journal of Emergency Medicine1865-13802025-04-011811510.1186/s12245-025-00883-7A rare case of upper gastrointestinal hemorrhage due to tuberculous lymphadenitis fistulized in the duodenumSouhaib Atri0Mahdi Hammami1Anis Belhadj2Faouzi Chebbi3Youssef Chaker4Montassar Kacem5Hopital la RabtaHopital la RabtaHopital Mahmoud El MatriHopital Mahmoud El MatriHopital la RabtaHopital la RabtaAbstract Introduction Abdominal tuberculosis is less prevalent than pulmonary tuberculosis. Tuberculous lymphadenitis accounts for fewer than 5% of abdominal cases. An unusual complication is the fistulization of a tuberculous lymph node into the digestive tract, with an even rarer association with upper gastrointestinal bleeding. Case Report A 63-year-old male with a history of rectal adenocarcinoma surgery presented with severe gastrointestinal bleeding that required multiple transfusions. Endoscopic attempts failed to locate the bleeding source, but CT angiogram revealed a hemorrhagic necrotic mesenteric lymph node with a fistula to the second part of the duodenum. The patient underwent surgery, which involved resecting the lymph nodes and disconnecting the fistula. Histopathological findings confirmed tuberculous mesenteric lymphadenitis, and the patient was subsequently started on HRZE therapy. Six months postoperatively, there was no recurrence of bleeding. Discussion Gastroduodenal tuberculosis is infrequent due to factors such as the high acidity of the gastric environment and limited lymphoid tissue. Symptoms may mimic other abdominal conditions, making diagnosis challenging. Common complications include gastric outlet obstruction and perforation, while gastrointestinal bleeding is rare. This case of hemorrhagic tuberculous lymphadenitis with fistulization highlights the need for a high index of suspicion and the role of imaging in diagnosing uncommon bleeding sources. While anti-tuberculosis therapy remains the primary treatment, surgery is warranted in cases involving refractory bleeding or fistulization. Conclusion This case emphasizes the importance of a multidisciplinary approach to abdominal tuberculosis with atypical presentations. Awareness of rare complications is essential for prompt diagnosis and management.https://doi.org/10.1186/s12245-025-00883-7FistulizationHemorrhageLymphadenitisTuberculosis
spellingShingle Souhaib Atri
Mahdi Hammami
Anis Belhadj
Faouzi Chebbi
Youssef Chaker
Montassar Kacem
A rare case of upper gastrointestinal hemorrhage due to tuberculous lymphadenitis fistulized in the duodenum
International Journal of Emergency Medicine
Fistulization
Hemorrhage
Lymphadenitis
Tuberculosis
title A rare case of upper gastrointestinal hemorrhage due to tuberculous lymphadenitis fistulized in the duodenum
title_full A rare case of upper gastrointestinal hemorrhage due to tuberculous lymphadenitis fistulized in the duodenum
title_fullStr A rare case of upper gastrointestinal hemorrhage due to tuberculous lymphadenitis fistulized in the duodenum
title_full_unstemmed A rare case of upper gastrointestinal hemorrhage due to tuberculous lymphadenitis fistulized in the duodenum
title_short A rare case of upper gastrointestinal hemorrhage due to tuberculous lymphadenitis fistulized in the duodenum
title_sort rare case of upper gastrointestinal hemorrhage due to tuberculous lymphadenitis fistulized in the duodenum
topic Fistulization
Hemorrhage
Lymphadenitis
Tuberculosis
url https://doi.org/10.1186/s12245-025-00883-7
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