Is reflux hypersensitivity truly a functional gastrointestinal disorder? A retrospective cross-sectional study.

Is reflux hypersensitivity truly a functional gastrointestinal disorder? A retrospective cross-sectional study.

<h4>Background</h4>According to Rome IV, reflux hypersensitivity (RH) represents a novel form of functional esophageal disorder. This study was designed to compare the clinical features of three types of endoscopic-negative heartburn: RH, nonerosive reflux disease (NERD), and functional...

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Main Authors: Yanping Wu, Siyu Liao, Tianyao Qu, Jiaxuan Zhou, Fei Dai, Bin Qin, Xiaoyu Xu, Jun Zhang, Yan Cheng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0316226
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