The influence of habitual tooth brushing frequency on individuals diagnosed with coronary artery disease

Abstract Coronary artery disease (CAD) is a prevalent and high-mortality condition globally. The awareness regarding adequate oral care in China was insufficient. This study investigates the outcomes of CAD patients in southwest China based on their tooth brushing frequency. A total of 841 CAD patie...

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Main Authors: Zihan Tang, Tian Qiu, Runfeng Ma, Ruoyu Wang, Bingqian Wang, Yiduo Lu, Bi Huang, Suxin Luo, Gang Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-01910-6
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Summary:Abstract Coronary artery disease (CAD) is a prevalent and high-mortality condition globally. The awareness regarding adequate oral care in China was insufficient. This study investigates the outcomes of CAD patients in southwest China based on their tooth brushing frequency. A total of 841 CAD patients were selected from a cohort of 32,709 residents. Over a four-year follow-up period, the incidence of three-point major adverse cardiovascular events (3P-MACEs) was evaluated. The results indicated that the hazard ratios (HR) with 95% confidence intervals (CIs) for 3P-MACEs among the three groups of tooth brushing frequency (twice, once, and thrice daily) were: reference, 1.61 (1.09–2.37) (p = 0.017), and 0.49 (0.15–1.62) (p = 0.241). Patients who brushed their teeth only once a day had a 1.71 (1.18–2.46) times higher risk compared to those who brushed twice or more daily (p = 0.004). In conclusion, insufficient tooth brushing frequency appears to be associated with a higher risk of adverse outcomes among CAD patients.
ISSN:2045-2322