Deciphering Squamous Cell Carcinoma Using Multidimensional Genomic Approaches
Squamous cell carcinomas (SqCCs) arise in a wide range of tissues including skin, lung, and oral mucosa. Although all SqCCs are epithelial in origin and share common nomenclature, these cancers differ greatly with respect to incidence, prognosis, and treatment. Current knowledge of genetic similari...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-01-01
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| Series: | Journal of Skin Cancer |
| Online Access: | http://dx.doi.org/10.1155/2011/541405 |
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| _version_ | 1849304260233134080 |
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| author | Ewan A. Gibb Katey S. S. Enfield Ivy F. L. Tsui Raj Chari Stephen Lam Carlos E. Alvarez Wan L. Lam |
| author_facet | Ewan A. Gibb Katey S. S. Enfield Ivy F. L. Tsui Raj Chari Stephen Lam Carlos E. Alvarez Wan L. Lam |
| author_sort | Ewan A. Gibb |
| collection | DOAJ |
| description | Squamous cell carcinomas (SqCCs) arise in a wide range of tissues including skin, lung, and oral mucosa. Although all SqCCs are epithelial in origin and share common nomenclature, these cancers differ greatly with respect to incidence, prognosis, and treatment. Current knowledge of genetic similarities and differences between SqCCs is insufficient to describe the biology of these cancers, which arise from diverse tissue origins. In this paper we provide a general overview of whole genome approaches for gene and pathway discovery and highlight the advancement of integrative genomics as a state-of-the-art technology in the study of SqCC genetics. |
| format | Article |
| id | doaj-art-195bef976dc14871ad0a5e4cb38d5dd8 |
| institution | Kabale University |
| issn | 2090-2905 2090-2913 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Skin Cancer |
| spelling | doaj-art-195bef976dc14871ad0a5e4cb38d5dd82025-08-20T03:55:45ZengWileyJournal of Skin Cancer2090-29052090-29132011-01-01201110.1155/2011/541405541405Deciphering Squamous Cell Carcinoma Using Multidimensional Genomic ApproachesEwan A. Gibb0Katey S. S. Enfield1Ivy F. L. Tsui2Raj Chari3Stephen Lam4Carlos E. Alvarez5Wan L. Lam6Department of Integrative Oncology, British Columbia Cancer Agency Research Centre, Vancouver BC, V5Z 1L3, CanadaDepartment of Integrative Oncology, British Columbia Cancer Agency Research Centre, Vancouver BC, V5Z 1L3, CanadaDepartment of Integrative Oncology, British Columbia Cancer Agency Research Centre, Vancouver BC, V5Z 1L3, CanadaDepartment of Integrative Oncology, British Columbia Cancer Agency Research Centre, Vancouver BC, V5Z 1L3, CanadaDepartment of Integrative Oncology, British Columbia Cancer Agency Research Centre, Vancouver BC, V5Z 1L3, CanadaDepartment of Pediatrics, Center for Molecular and Human Genetics, The Research Institute at Nationwide Children’s Hospital, Columbus, OH 43205, USADepartment of Integrative Oncology, British Columbia Cancer Agency Research Centre, Vancouver BC, V5Z 1L3, CanadaSquamous cell carcinomas (SqCCs) arise in a wide range of tissues including skin, lung, and oral mucosa. Although all SqCCs are epithelial in origin and share common nomenclature, these cancers differ greatly with respect to incidence, prognosis, and treatment. Current knowledge of genetic similarities and differences between SqCCs is insufficient to describe the biology of these cancers, which arise from diverse tissue origins. In this paper we provide a general overview of whole genome approaches for gene and pathway discovery and highlight the advancement of integrative genomics as a state-of-the-art technology in the study of SqCC genetics.http://dx.doi.org/10.1155/2011/541405 |
| spellingShingle | Ewan A. Gibb Katey S. S. Enfield Ivy F. L. Tsui Raj Chari Stephen Lam Carlos E. Alvarez Wan L. Lam Deciphering Squamous Cell Carcinoma Using Multidimensional Genomic Approaches Journal of Skin Cancer |
| title | Deciphering Squamous Cell Carcinoma Using Multidimensional Genomic Approaches |
| title_full | Deciphering Squamous Cell Carcinoma Using Multidimensional Genomic Approaches |
| title_fullStr | Deciphering Squamous Cell Carcinoma Using Multidimensional Genomic Approaches |
| title_full_unstemmed | Deciphering Squamous Cell Carcinoma Using Multidimensional Genomic Approaches |
| title_short | Deciphering Squamous Cell Carcinoma Using Multidimensional Genomic Approaches |
| title_sort | deciphering squamous cell carcinoma using multidimensional genomic approaches |
| url | http://dx.doi.org/10.1155/2011/541405 |
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