Osr1 Interacts Synergistically with Wt1 to Regulate Kidney Organogenesis.
Renal hypoplasia is a common cause of pediatric renal failure and several adult-onset diseases. Recent studies have associated a variant of the OSR1 gene with reduction of newborn kidney size and function in heterozygotes and neonatal lethality with kidney defects in homozygotes. How OSR1 regulates...
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| Main Authors: | Jingyue Xu, Han Liu, Ok Hee Chai, Yu Lan, Rulang Jiang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2016-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0159597 |
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