Systematic study of drug distribution profiles of different nanocarriers in the skin layers: a more accurate and targeted delivery

Systematic study of drug distribution profiles of different nanocarriers in the skin layers: a more accurate and targeted delivery

The aim of this work was to evaluate the skin distributions of two drugs with different logarithm of the distribution coefficient (Log D) values. Melatonin (MEL; Log D 1.74) and benzophenone-3 (BZA-3; Log D 3.88) lipid core nanocapsules (LNCs) were prepared with poly(e-caprolactone) (PCL) of differ...

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Bibliographic Details
Main Authors: Manuela Gonçalves, Kelly Cristine Zatta, Adriana Raffin Pohlmann, Silvia Stanisçuaski Guterres
Format: Article
Language:English
Published: Universidade Federal do Rio Grande do Sul 2024-12-01
Series:Drug Analytical Research
Subjects:
Lipid core nanocapsule
nanoemulsion
Log D
skin penetration
skin permeation
in vitro release
Online Access:https://seer.ufrgs.br/rita/citati/index.php/dar/article/view/143983
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