HNRNPH1 promotes autophagy to inhibit the development of lung adenocarcinoma via the HSP90AB1/MAP1LC3B axis

HNRNPH1 promotes autophagy to inhibit the development of lung adenocarcinoma via the HSP90AB1/MAP1LC3B axis

Abstract Background Lung adenocarcinoma (LUAD) is a prevalent subtype of lung cancer (LC) whose progression is regulated by multiple genes. This study sought to find the impact and mechanism of HNRNPH1 on LUAD. Methods The expression and role of HSP90AB1, HNRNPH1, and autophagy-related protein MAP1L...

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Bibliographic Details
Main Authors: Rong Li, Fen Li, Qian Liu, Xu Wu, Xiaowu Tan
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Respiratory Research
Subjects:
Lung adenocarcinoma
HNRNPH1
HSP90AB1
MAP1LC3B
Autophagy
Online Access:https://doi.org/10.1186/s12931-025-03280-z
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