The Clinical Features and Helicobacter pylori Eradication Therapy in Lymphofollicular Gastritis: A Single Center Experience
Background/Aims: Lymphofollicular gastritis (LFG) is defined as antral gastritis with endoscopic findings characterized by a miliary pattern resembling “goose flesh”. We aimed to analyze the clinical features of LFG and the utility of Helicobacter pylori eradication therapy in LFG. Materials and Met...
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Korean College of Helicobacter and Upper Gastrointestinal Research
2016-12-01
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| Series: | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
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| Online Access: | http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2016.16.4.221 |
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| author | Hong Ju An Nam Hun Lee Chung Kang Ho Young Song Joon Seung Yang Eun Jeong Kim Young Ho Seo |
| author_facet | Hong Ju An Nam Hun Lee Chung Kang Ho Young Song Joon Seung Yang Eun Jeong Kim Young Ho Seo |
| author_sort | Hong Ju An |
| collection | DOAJ |
| description | Background/Aims: Lymphofollicular gastritis (LFG) is defined as antral gastritis with endoscopic findings characterized by a miliary pattern resembling “goose flesh”. We aimed to analyze the clinical features of LFG and the utility of Helicobacter pylori eradication therapy in LFG. Materials and Methods: Patients with LFG, regardless of upper gastrointestinal symptoms (7 men, 28 women; age range, 21∼67 years), were examined for H. pylori using the CLO test during endoscopy. One specimen was obtained from the greater curvatures of the lower body and the antrum. Clinical features were compared according to H. pylori-positive status. Results: Among 35 patients with LFG, 31 (88.6%) were infected with H. pylori. LFG predominantly affected young women (28/35, 80.0%; mean age, 43.73 years). One case of gastric cancer with H. pylori-positive LFG was found. H. pylori eradication rate in LFG patients was low (3/12, 25.0%). Conclusions: LFG is closely associated with H. pylori infection and predominantly affects women and young adults. Future studies are needed to determine whether H. pylori eradication reduces the risk of gastric cancer. |
| format | Article |
| id | doaj-art-1941abceebc04eecafa82fb610682484 |
| institution | DOAJ |
| issn | 1738-3331 |
| language | English |
| publishDate | 2016-12-01 |
| publisher | Korean College of Helicobacter and Upper Gastrointestinal Research |
| record_format | Article |
| series | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
| spelling | doaj-art-1941abceebc04eecafa82fb6106824842025-08-20T02:41:56ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312016-12-0116422122510.7704/kjhugr.2016.16.4.221kjhugr.2016.16.4.221The Clinical Features and Helicobacter pylori Eradication Therapy in Lymphofollicular Gastritis: A Single Center ExperienceHong Ju An0Nam Hun Lee1Chung Kang2Ho Young Song3Joon Seung Yang4Eun Jeong Kim5Young Ho Seo6Division of Gastroenterology, Department of Internal Medicine, Gwangju Veterans Hospital, Gwangju, KoreaDivision of Gastroenterology, Department of Internal Medicine, Gwangju Veterans Hospital, Gwangju, KoreaDivision of Gastroenterology, Department of Internal Medicine, Gwangju Veterans Hospital, Gwangju, KoreaDivision of Gastroenterology, Department of Internal Medicine, Gwangju Veterans Hospital, Gwangju, KoreaDivision of Gastroenterology, Department of Internal Medicine, Gwangju Veterans Hospital, Gwangju, KoreaDivision of Gastroenterology, Department of Internal Medicine, Gwangju Veterans Hospital, Gwangju, KoreaDivision of Gastroenterology, Department of Internal Medicine, Gwangju Veterans Hospital, Gwangju, KoreaBackground/Aims: Lymphofollicular gastritis (LFG) is defined as antral gastritis with endoscopic findings characterized by a miliary pattern resembling “goose flesh”. We aimed to analyze the clinical features of LFG and the utility of Helicobacter pylori eradication therapy in LFG. Materials and Methods: Patients with LFG, regardless of upper gastrointestinal symptoms (7 men, 28 women; age range, 21∼67 years), were examined for H. pylori using the CLO test during endoscopy. One specimen was obtained from the greater curvatures of the lower body and the antrum. Clinical features were compared according to H. pylori-positive status. Results: Among 35 patients with LFG, 31 (88.6%) were infected with H. pylori. LFG predominantly affected young women (28/35, 80.0%; mean age, 43.73 years). One case of gastric cancer with H. pylori-positive LFG was found. H. pylori eradication rate in LFG patients was low (3/12, 25.0%). Conclusions: LFG is closely associated with H. pylori infection and predominantly affects women and young adults. Future studies are needed to determine whether H. pylori eradication reduces the risk of gastric cancer.http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2016.16.4.221Lymphofollicular gastritisHelicobacter pyloriEradication therapy |
| spellingShingle | Hong Ju An Nam Hun Lee Chung Kang Ho Young Song Joon Seung Yang Eun Jeong Kim Young Ho Seo The Clinical Features and Helicobacter pylori Eradication Therapy in Lymphofollicular Gastritis: A Single Center Experience The Korean Journal of Helicobacter and Upper Gastrointestinal Research Lymphofollicular gastritis Helicobacter pylori Eradication therapy |
| title | The Clinical Features and Helicobacter pylori Eradication Therapy in Lymphofollicular Gastritis: A Single Center Experience |
| title_full | The Clinical Features and Helicobacter pylori Eradication Therapy in Lymphofollicular Gastritis: A Single Center Experience |
| title_fullStr | The Clinical Features and Helicobacter pylori Eradication Therapy in Lymphofollicular Gastritis: A Single Center Experience |
| title_full_unstemmed | The Clinical Features and Helicobacter pylori Eradication Therapy in Lymphofollicular Gastritis: A Single Center Experience |
| title_short | The Clinical Features and Helicobacter pylori Eradication Therapy in Lymphofollicular Gastritis: A Single Center Experience |
| title_sort | clinical features and helicobacter pylori eradication therapy in lymphofollicular gastritis a single center experience |
| topic | Lymphofollicular gastritis Helicobacter pylori Eradication therapy |
| url | http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2016.16.4.221 |
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