The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development.

The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development.

The corpus callosum (CC) is the major commissure that bridges the cerebral hemispheres. Agenesis of the CC is associated with human ciliopathies, but the origin of this default is unclear. Regulatory Factor X3 (RFX3) is a transcription factor involved in the control of ciliogenesis, and Rfx3-deficie...

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Main Authors: Carine Benadiba, Dario Magnani, Mathieu Niquille, Laurette Morlé, Delphine Valloton, Homaira Nawabi, Aouatef Ait-Lounis, Belkacem Otsmane, Walter Reith, Thomas Theil, Jean-Pierre Hornung, Cécile Lebrand, Bénédicte Durand
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002606&type=printable
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