Dissecting cell-free DNA fragmentation variation in tumors using cell line-derived xenograft mouse.

Dissecting cell-free DNA fragmentation variation in tumors using cell line-derived xenograft mouse.

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Cell-free DNA (cfDNA) is increasingly studied for its diverse applications in non-invasive detection. Non-randomly cleaved by nucleases and released into the bloodstream, cfDNA exhibits a variety of intrinsic fragmentation patterns indicative of cell status. Particularly, these fragmentation pattern...

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Bibliographic Details
Main Authors: Ruiqing Fu, He Amy Su, Yi Zhao, Yafei Tian, Hongyan Chen, Daru Lu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0327483
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