Ferroptosis spreads to neighboring cells via plasma membrane contacts

Abstract Ferroptosis is a lytic, iron-dependent form of regulated cell death characterized by excessive lipid peroxidation and associated with necrosis spread in diseased tissues through unknown mechanisms. Using a novel optogenetic system for light-driven ferroptosis induction via degradation of th...

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Bibliographic Details
Main Authors: Bernhard F. Roeck, Sara Lotfipour Nasudivar, Michael R. H. Vorndran, Lena Schueller, F. Isil Yapici, Matthias Rübsam, Silvia von Karstedt, Carien M. Niessen, Ana J. Garcia-Saez
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-58175-w
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