Antibacterial Activity of Silver-Modified CuO Nanoparticle-Coated Masks

A green and cost-effective sonochemical synthetic method was followed for coating silver-modified copper oxide (Ag-CuO) nanoparticles (NPs) on disposable surgical mask. The NP-coated masks were systematically characterized using XRD and FT-IR for understanding the structural and surface functionalit...

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Main Authors: Tanuja Udawant, Prajkta Thorat, Payal Thapa, Manali Patel, Saroj Shekhawat, Roshni Patel, Ankit Sudhir, Om Hudka, Indra Neel Pulidindi, Archana Deokar
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Bioengineering
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Online Access:https://www.mdpi.com/2306-5354/11/12/1234
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author Tanuja Udawant
Prajkta Thorat
Payal Thapa
Manali Patel
Saroj Shekhawat
Roshni Patel
Ankit Sudhir
Om Hudka
Indra Neel Pulidindi
Archana Deokar
author_facet Tanuja Udawant
Prajkta Thorat
Payal Thapa
Manali Patel
Saroj Shekhawat
Roshni Patel
Ankit Sudhir
Om Hudka
Indra Neel Pulidindi
Archana Deokar
author_sort Tanuja Udawant
collection DOAJ
description A green and cost-effective sonochemical synthetic method was followed for coating silver-modified copper oxide (Ag-CuO) nanoparticles (NPs) on disposable surgical mask. The NP-coated masks were systematically characterized using XRD and FT-IR for understanding the structural and surface functionalities. In addition, the field emission scanning electron microscopy (FE-SEM) analysis showed the homogeneous coating of Ag-CuO NPs over the mask fibers. The average particle size of Ag-CuO was found to be ~70 nm. The NP-coated masks are useful to combat a broad range of bacterial species by taking the unique advantage of the synergistic effect of Ag and metal oxide (CuO and ZnO) NPs for the generation of reactive oxygen species (ROS). Zone of inhibition (ZoI) studies demonstrated antibacterial activity against both Gram-positive <i>S. aureus</i> and Gram-negative <i>E. coli</i> bacteria, probably due to the elevated production of ROS by the defect structure of the Ag-modified metal oxide NPs. The material was found to be effective against both airborne and soil-borne bacteria. We repeat that this paper deals only with the killing effect of the nanoparticles (Ag-modified CuO) on bacteria, and no studies on viral species are performed.
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issn 2306-5354
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publishDate 2024-12-01
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spelling doaj-art-1920143aa9be4b96a7ee4ea4fb2f760e2025-08-20T02:00:51ZengMDPI AGBioengineering2306-53542024-12-011112123410.3390/bioengineering11121234Antibacterial Activity of Silver-Modified CuO Nanoparticle-Coated MasksTanuja Udawant0Prajkta Thorat1Payal Thapa2Manali Patel3Saroj Shekhawat4Roshni Patel5Ankit Sudhir6Om Hudka7Indra Neel Pulidindi8Archana Deokar9Modern College of Arts, Science, and Commerce, Pune 411005, IndiaModern College of Arts, Science, and Commerce, Pune 411005, IndiaDepartment of Life Sciences, School of Science, Gujarat State Fertilizers and Chemicals University, Vadodara 391750, IndiaDepartment of Life Sciences, School of Science, Gujarat State Fertilizers and Chemicals University, Vadodara 391750, IndiaDepartment of Life Sciences, School of Science, Gujarat State Fertilizers and Chemicals University, Vadodara 391750, IndiaDepartment of Life Sciences, School of Science, Gujarat State Fertilizers and Chemicals University, Vadodara 391750, IndiaDepartment of Life Sciences, School of Science, Gujarat State Fertilizers and Chemicals University, Vadodara 391750, IndiaDepartment of Chemical Sciences, School of Science, Gujarat State Fertilizers and Chemicals University, Vadodara 391750, IndiaJesus’ Scientific Consultancy for Industrial and Academic Research (JSCIAR), Tharamani 600113, IndiaModern College of Arts, Science, and Commerce, Pune 411005, IndiaA green and cost-effective sonochemical synthetic method was followed for coating silver-modified copper oxide (Ag-CuO) nanoparticles (NPs) on disposable surgical mask. The NP-coated masks were systematically characterized using XRD and FT-IR for understanding the structural and surface functionalities. In addition, the field emission scanning electron microscopy (FE-SEM) analysis showed the homogeneous coating of Ag-CuO NPs over the mask fibers. The average particle size of Ag-CuO was found to be ~70 nm. The NP-coated masks are useful to combat a broad range of bacterial species by taking the unique advantage of the synergistic effect of Ag and metal oxide (CuO and ZnO) NPs for the generation of reactive oxygen species (ROS). Zone of inhibition (ZoI) studies demonstrated antibacterial activity against both Gram-positive <i>S. aureus</i> and Gram-negative <i>E. coli</i> bacteria, probably due to the elevated production of ROS by the defect structure of the Ag-modified metal oxide NPs. The material was found to be effective against both airborne and soil-borne bacteria. We repeat that this paper deals only with the killing effect of the nanoparticles (Ag-modified CuO) on bacteria, and no studies on viral species are performed.https://www.mdpi.com/2306-5354/11/12/1234Ag-CuOAg-ZnOnanoparticlessonicationairborne bacteriamasks
spellingShingle Tanuja Udawant
Prajkta Thorat
Payal Thapa
Manali Patel
Saroj Shekhawat
Roshni Patel
Ankit Sudhir
Om Hudka
Indra Neel Pulidindi
Archana Deokar
Antibacterial Activity of Silver-Modified CuO Nanoparticle-Coated Masks
Bioengineering
Ag-CuO
Ag-ZnO
nanoparticles
sonication
airborne bacteria
masks
title Antibacterial Activity of Silver-Modified CuO Nanoparticle-Coated Masks
title_full Antibacterial Activity of Silver-Modified CuO Nanoparticle-Coated Masks
title_fullStr Antibacterial Activity of Silver-Modified CuO Nanoparticle-Coated Masks
title_full_unstemmed Antibacterial Activity of Silver-Modified CuO Nanoparticle-Coated Masks
title_short Antibacterial Activity of Silver-Modified CuO Nanoparticle-Coated Masks
title_sort antibacterial activity of silver modified cuo nanoparticle coated masks
topic Ag-CuO
Ag-ZnO
nanoparticles
sonication
airborne bacteria
masks
url https://www.mdpi.com/2306-5354/11/12/1234
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