Small intestinal bacterial overgrowth in patients with systemic sclerosis
Small intestinal bacterial overgrowth (SIBO) is common in patients with systemic sclerosis (SSc) yet often goes underrecognized in clinical practice. In patients with SSc, untreated SIBO may result in marked morbidity and possible mortality. The pathogenesis of SIBO is multifactorial and relates to...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2017-01-01
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| Series: | Indian Journal of Rheumatology |
| Subjects: | |
| Online Access: | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2017;volume=12;issue=6;spage=167;epage=170;aulast=Rawn |
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| _version_ | 1832542995352649728 |
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| author | Saara Rawn Natalia Pitman Karen Beattie Ava Bazzaz Maggie Larche |
| author_facet | Saara Rawn Natalia Pitman Karen Beattie Ava Bazzaz Maggie Larche |
| author_sort | Saara Rawn |
| collection | DOAJ |
| description | Small intestinal bacterial overgrowth (SIBO) is common in patients with systemic sclerosis (SSc) yet often goes underrecognized in clinical practice. In patients with SSc, untreated SIBO may result in marked morbidity and possible mortality. The pathogenesis of SIBO is multifactorial and relates to immune dysregulation, vasculopathy, and dysmotility. This article reviews various diagnostic approaches and therapeutic options for SIBO. Treatment modalities mainly include prokinetics, probiotics, and antibiotics. |
| format | Article |
| id | doaj-art-191f43e547cb483f9bac428fb1f27bf1 |
| institution | Kabale University |
| issn | 0973-3698 0973-3701 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Indian Journal of Rheumatology |
| spelling | doaj-art-191f43e547cb483f9bac428fb1f27bf12025-02-03T11:54:50ZengSAGE PublishingIndian Journal of Rheumatology0973-36980973-37012017-01-01126167170Small intestinal bacterial overgrowth in patients with systemic sclerosisSaara RawnNatalia PitmanKaren BeattieAva BazzazMaggie LarcheSmall intestinal bacterial overgrowth (SIBO) is common in patients with systemic sclerosis (SSc) yet often goes underrecognized in clinical practice. In patients with SSc, untreated SIBO may result in marked morbidity and possible mortality. The pathogenesis of SIBO is multifactorial and relates to immune dysregulation, vasculopathy, and dysmotility. This article reviews various diagnostic approaches and therapeutic options for SIBO. Treatment modalities mainly include prokinetics, probiotics, and antibiotics.http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2017;volume=12;issue=6;spage=167;epage=170;aulast=RawnantibioticsGastrointestinal symptomsprobioticsprokineticsSclerodermaSmall bowel bacterial overgrowth |
| spellingShingle | Saara Rawn Natalia Pitman Karen Beattie Ava Bazzaz Maggie Larche Small intestinal bacterial overgrowth in patients with systemic sclerosis Indian Journal of Rheumatology antibiotics Gastrointestinal symptoms probiotics prokinetics Scleroderma Small bowel bacterial overgrowth |
| title | Small intestinal bacterial overgrowth in patients with systemic sclerosis |
| title_full | Small intestinal bacterial overgrowth in patients with systemic sclerosis |
| title_fullStr | Small intestinal bacterial overgrowth in patients with systemic sclerosis |
| title_full_unstemmed | Small intestinal bacterial overgrowth in patients with systemic sclerosis |
| title_short | Small intestinal bacterial overgrowth in patients with systemic sclerosis |
| title_sort | small intestinal bacterial overgrowth in patients with systemic sclerosis |
| topic | antibiotics Gastrointestinal symptoms probiotics prokinetics Scleroderma Small bowel bacterial overgrowth |
| url | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2017;volume=12;issue=6;spage=167;epage=170;aulast=Rawn |
| work_keys_str_mv | AT saararawn smallintestinalbacterialovergrowthinpatientswithsystemicsclerosis AT nataliapitman smallintestinalbacterialovergrowthinpatientswithsystemicsclerosis AT karenbeattie smallintestinalbacterialovergrowthinpatientswithsystemicsclerosis AT avabazzaz smallintestinalbacterialovergrowthinpatientswithsystemicsclerosis AT maggielarche smallintestinalbacterialovergrowthinpatientswithsystemicsclerosis |