Non-Islet Cell Tumor Hypoglycemia Secondary to a 20 cm Intra-Abdominal Leiomyoma in a Male Patient: A Case Report and Literature Review

Non-islet cell tumor hypoglycemia (NICTH) is a rare clinical entity associated with large mesenchymal tumors. Its pathogenesis is most commonly mediated by tumor overproduction of “big” insulin-like growth factor-2. Here, we present a 54-year-old male who presented with noninsulin-mediated hypoglyce...

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Main Authors: Michelle D. Lippincott, James D. McDonald, Marilyn M. Bui, Ricardo J. Gonzalez, Rachel K. Voss
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Surgery
Online Access:http://dx.doi.org/10.1155/2024/6651107
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author Michelle D. Lippincott
James D. McDonald
Marilyn M. Bui
Ricardo J. Gonzalez
Rachel K. Voss
author_facet Michelle D. Lippincott
James D. McDonald
Marilyn M. Bui
Ricardo J. Gonzalez
Rachel K. Voss
author_sort Michelle D. Lippincott
collection DOAJ
description Non-islet cell tumor hypoglycemia (NICTH) is a rare clinical entity associated with large mesenchymal tumors. Its pathogenesis is most commonly mediated by tumor overproduction of “big” insulin-like growth factor-2. Here, we present a 54-year-old male who presented with noninsulin-mediated hypoglycemia and a 20 cm intra-abdominal leiomyoma. His hypoglycemic episodes resolved after the resection of his tumor. To our knowledge, this is the only documented case in the English literature of NICTH associated with leiomyoma in a male patient. NICTH due to a benign leiomyoma should be in the differential diagnosis for any patient with hypoglycemia and an abdominal mass.
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language English
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series Case Reports in Surgery
spelling doaj-art-19160bcd905346f7a41034f99b2fe9bb2025-08-20T02:02:09ZengWileyCase Reports in Surgery2090-69192024-01-01202410.1155/2024/6651107Non-Islet Cell Tumor Hypoglycemia Secondary to a 20 cm Intra-Abdominal Leiomyoma in a Male Patient: A Case Report and Literature ReviewMichelle D. Lippincott0James D. McDonald1Marilyn M. Bui2Ricardo J. Gonzalez3Rachel K. Voss4Department of SurgeryDepartment of Sarcoma OncologyDepartment of PathologyDepartment of Sarcoma OncologyDepartment of Sarcoma OncologyNon-islet cell tumor hypoglycemia (NICTH) is a rare clinical entity associated with large mesenchymal tumors. Its pathogenesis is most commonly mediated by tumor overproduction of “big” insulin-like growth factor-2. Here, we present a 54-year-old male who presented with noninsulin-mediated hypoglycemia and a 20 cm intra-abdominal leiomyoma. His hypoglycemic episodes resolved after the resection of his tumor. To our knowledge, this is the only documented case in the English literature of NICTH associated with leiomyoma in a male patient. NICTH due to a benign leiomyoma should be in the differential diagnosis for any patient with hypoglycemia and an abdominal mass.http://dx.doi.org/10.1155/2024/6651107
spellingShingle Michelle D. Lippincott
James D. McDonald
Marilyn M. Bui
Ricardo J. Gonzalez
Rachel K. Voss
Non-Islet Cell Tumor Hypoglycemia Secondary to a 20 cm Intra-Abdominal Leiomyoma in a Male Patient: A Case Report and Literature Review
Case Reports in Surgery
title Non-Islet Cell Tumor Hypoglycemia Secondary to a 20 cm Intra-Abdominal Leiomyoma in a Male Patient: A Case Report and Literature Review
title_full Non-Islet Cell Tumor Hypoglycemia Secondary to a 20 cm Intra-Abdominal Leiomyoma in a Male Patient: A Case Report and Literature Review
title_fullStr Non-Islet Cell Tumor Hypoglycemia Secondary to a 20 cm Intra-Abdominal Leiomyoma in a Male Patient: A Case Report and Literature Review
title_full_unstemmed Non-Islet Cell Tumor Hypoglycemia Secondary to a 20 cm Intra-Abdominal Leiomyoma in a Male Patient: A Case Report and Literature Review
title_short Non-Islet Cell Tumor Hypoglycemia Secondary to a 20 cm Intra-Abdominal Leiomyoma in a Male Patient: A Case Report and Literature Review
title_sort non islet cell tumor hypoglycemia secondary to a 20 cm intra abdominal leiomyoma in a male patient a case report and literature review
url http://dx.doi.org/10.1155/2024/6651107
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