An agent-based model to assess the impact of shared staff and occupancy rate on infectious disease burden in nursing homes

Abstract Infectious diseases can propagate between nursing homes through asymptomatic staff members who are employed at multiple facilities. However, the transmission dynamics of infections, both within individual nursing homes and across facilities, has been less investigated. To fill this gap, we...

Full description

Saved in:
Bibliographic Details
Main Authors: Kiel Corkran, Jose Pablo Gómez-Vázquez, Arash Arjmand, Miriam Nuño, Majid Bani-Yaghoub
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Infectious Diseases
Subjects:
Online Access:https://doi.org/10.1186/s12879-025-10786-w
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850042416783949824
author Kiel Corkran
Jose Pablo Gómez-Vázquez
Arash Arjmand
Miriam Nuño
Majid Bani-Yaghoub
author_facet Kiel Corkran
Jose Pablo Gómez-Vázquez
Arash Arjmand
Miriam Nuño
Majid Bani-Yaghoub
author_sort Kiel Corkran
collection DOAJ
description Abstract Infectious diseases can propagate between nursing homes through asymptomatic staff members who are employed at multiple facilities. However, the transmission dynamics of infections, both within individual nursing homes and across facilities, has been less investigated. To fill this gap, we developed an agent-based model of two nursing homes extendible to a network of n nursing homes connected with different percentages of shared staff. Focusing on the outbreaks of COVID-19 in U.S. nursing homes, we calibrated the model according to the COVID-19 prevalence data and estimated levels of shared staff for each State. The model simulations indicate that reducing the percentage of shared staff below 5% plays a significant role in controlling the spread of infection from one nursing home to another through personal protective equipment usage, rapid testing, and vaccination. As the percentage of shared staff increases to more than 30%, these measures become less effective, and the mean prevalence of infection reaches a steady state in both nursing homes. The hazard ratios for infection and mortality indicate that nursing homes with higher occupancy rates are more significantly affected by increased staff-sharing percentages. In conclusion, the burden of infection significantly increases with greater staff sharing between nursing homes, particularly in high-occupancy facilities, where transmission dynamics are amplified due to greater resident density and staff interactions.
format Article
id doaj-art-19105d127d02473c9e579bbafc4ec2a1
institution DOAJ
issn 1471-2334
language English
publishDate 2025-04-01
publisher BMC
record_format Article
series BMC Infectious Diseases
spelling doaj-art-19105d127d02473c9e579bbafc4ec2a12025-08-20T02:55:35ZengBMCBMC Infectious Diseases1471-23342025-04-0125111510.1186/s12879-025-10786-wAn agent-based model to assess the impact of shared staff and occupancy rate on infectious disease burden in nursing homesKiel Corkran0Jose Pablo Gómez-Vázquez1Arash Arjmand2Miriam Nuño3Majid Bani-Yaghoub4Division of Computing, Analytics and Mathematics, School of Science and Engineering, University of Missouri-Kansas CityDepartment of Veterinary Medicine and Epidemiology, University of California DavisDivision of Computing, Analytics and Mathematics, School of Science and Engineering, University of Missouri-Kansas CityDepartment of Public Health Sciences, University of California DavisDivision of Computing, Analytics and Mathematics, School of Science and Engineering, University of Missouri-Kansas CityAbstract Infectious diseases can propagate between nursing homes through asymptomatic staff members who are employed at multiple facilities. However, the transmission dynamics of infections, both within individual nursing homes and across facilities, has been less investigated. To fill this gap, we developed an agent-based model of two nursing homes extendible to a network of n nursing homes connected with different percentages of shared staff. Focusing on the outbreaks of COVID-19 in U.S. nursing homes, we calibrated the model according to the COVID-19 prevalence data and estimated levels of shared staff for each State. The model simulations indicate that reducing the percentage of shared staff below 5% plays a significant role in controlling the spread of infection from one nursing home to another through personal protective equipment usage, rapid testing, and vaccination. As the percentage of shared staff increases to more than 30%, these measures become less effective, and the mean prevalence of infection reaches a steady state in both nursing homes. The hazard ratios for infection and mortality indicate that nursing homes with higher occupancy rates are more significantly affected by increased staff-sharing percentages. In conclusion, the burden of infection significantly increases with greater staff sharing between nursing homes, particularly in high-occupancy facilities, where transmission dynamics are amplified due to greater resident density and staff interactions.https://doi.org/10.1186/s12879-025-10786-wAgent-based modelNursing homeShared staffCOVID-19InfectionGAMA
spellingShingle Kiel Corkran
Jose Pablo Gómez-Vázquez
Arash Arjmand
Miriam Nuño
Majid Bani-Yaghoub
An agent-based model to assess the impact of shared staff and occupancy rate on infectious disease burden in nursing homes
BMC Infectious Diseases
Agent-based model
Nursing home
Shared staff
COVID-19
Infection
GAMA
title An agent-based model to assess the impact of shared staff and occupancy rate on infectious disease burden in nursing homes
title_full An agent-based model to assess the impact of shared staff and occupancy rate on infectious disease burden in nursing homes
title_fullStr An agent-based model to assess the impact of shared staff and occupancy rate on infectious disease burden in nursing homes
title_full_unstemmed An agent-based model to assess the impact of shared staff and occupancy rate on infectious disease burden in nursing homes
title_short An agent-based model to assess the impact of shared staff and occupancy rate on infectious disease burden in nursing homes
title_sort agent based model to assess the impact of shared staff and occupancy rate on infectious disease burden in nursing homes
topic Agent-based model
Nursing home
Shared staff
COVID-19
Infection
GAMA
url https://doi.org/10.1186/s12879-025-10786-w
work_keys_str_mv AT kielcorkran anagentbasedmodeltoassesstheimpactofsharedstaffandoccupancyrateoninfectiousdiseaseburdeninnursinghomes
AT josepablogomezvazquez anagentbasedmodeltoassesstheimpactofsharedstaffandoccupancyrateoninfectiousdiseaseburdeninnursinghomes
AT arasharjmand anagentbasedmodeltoassesstheimpactofsharedstaffandoccupancyrateoninfectiousdiseaseburdeninnursinghomes
AT miriamnuno anagentbasedmodeltoassesstheimpactofsharedstaffandoccupancyrateoninfectiousdiseaseburdeninnursinghomes
AT majidbaniyaghoub anagentbasedmodeltoassesstheimpactofsharedstaffandoccupancyrateoninfectiousdiseaseburdeninnursinghomes
AT kielcorkran agentbasedmodeltoassesstheimpactofsharedstaffandoccupancyrateoninfectiousdiseaseburdeninnursinghomes
AT josepablogomezvazquez agentbasedmodeltoassesstheimpactofsharedstaffandoccupancyrateoninfectiousdiseaseburdeninnursinghomes
AT arasharjmand agentbasedmodeltoassesstheimpactofsharedstaffandoccupancyrateoninfectiousdiseaseburdeninnursinghomes
AT miriamnuno agentbasedmodeltoassesstheimpactofsharedstaffandoccupancyrateoninfectiousdiseaseburdeninnursinghomes
AT majidbaniyaghoub agentbasedmodeltoassesstheimpactofsharedstaffandoccupancyrateoninfectiousdiseaseburdeninnursinghomes