Histone Acetyltransferase MOF-Mediated AURKB K215 Acetylation Drives Breast Cancer Cell Proliferation via c-MYC Stabilization

Histone Acetyltransferase MOF-Mediated AURKB K215 Acetylation Drives Breast Cancer Cell Proliferation via c-MYC Stabilization

Aurora kinase B (AURKB), a serine/threonine protein kinase, is essential for accurate chromosome segregation and cytokinesis during mitosis. Dysregulation of AURKB, often characterized by its overexpression, has been implicated in various malignancies, including breast cancer. However, the mechanism...

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Bibliographic Details
Main Authors: Yujuan Miao, Na Zhang, Fuqing Li, Fei Wang, Yuyang Chen, Fuqiang Li, Xueli Cui, Qingzhi Zhao, Yong Cai, Jingji Jin
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Cells
Subjects:
AURKB
MOF
histone acetyltransferase
acetylation
cell proliferation
Online Access:https://www.mdpi.com/2073-4409/14/14/1100
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