Post-COVID-19 Syndrome and Related Dysautonomia: Reduced Quality of Life, Increased Anxiety and Manifestation of Depressive Symptoms: Evidence from Greece
Background: Post-COVID-19 syndrome affects a significant number of SARS-CoV-2 infected individuals, even in asymptomatic cases causing several neurological and neuropsychiatric symptoms and signs. Materials and Methods: An online cross-sectional study with a convenience sample was conducted in Gree...
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Vilnius University Press
2023-10-01
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| Series: | Acta Medica Lituanica |
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| Online Access: | https://www.journals.vu.lt/AML/article/view/31683 |
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| author | Petros Galanis Aglaia Katsiroumpa Irene Vraka Katerina Kosiara Olga Siskou Olympia Konstantakopoulou Theodoros Katsoulas Parisis Gallos Daphne Kaitelidou |
| author_facet | Petros Galanis Aglaia Katsiroumpa Irene Vraka Katerina Kosiara Olga Siskou Olympia Konstantakopoulou Theodoros Katsoulas Parisis Gallos Daphne Kaitelidou |
| author_sort | Petros Galanis |
| collection | DOAJ |
| description |
Background: Post-COVID-19 syndrome affects a significant number of SARS-CoV-2 infected individuals, even in asymptomatic cases causing several neurological and neuropsychiatric symptoms and signs.
Materials and Methods: An online cross-sectional study with a convenience sample was conducted in Greece from November 2022 to January 2023. We measured the demographic and clinical characteristics of patients with post-COVID-19 dysautonomia in terms of the quality of life with the EQ-5D-3L, and anxiety and depressive symptoms by employing Patient Health Questionnaire-4.
Results: The study population included 122 patients with post-COVID-19 syndrome. One out of four patients (27.8%) manifested post-COVID-19 dysautonomia, while the mean duration of COVID-19 symptoms was 11.6 months. Anxiety and depressive symptoms were worse after the post-COVID-19 syndrome (p<0.001 in both cases). A statistically significant reduction in quality of life was observed among patients after the post-COVID-19 syndrome (p<0.001 for both EQ-5D-3L index value and EQ-5D-3L VAS). Post-COVID-19 dysautonomia increased depression symptoms after developing the post-COVID-19 syndrome (p=0.02). We found a negative relationship between the duration of COVID-19 symptoms and the quality of life (p<0.001). Moreover, our results showed that depressive symptoms were more common among females after the post-COVID-19 syndrome (p=0.01). Also, the quality of life was lower among females than males (p=0.004 for EQ-5D-3L index value, and p=0.007 for EQ-5D-3L VAS).
Conclusions: Our results suggest that post-COVID-19 syndrome causes a tremendous impact on the patients’ quality of life and mental health. In addition, we found that the groups most psychologically affected were patients with post-COVID-19 dysautonomia, females, and patients with a longer duration of symptoms. Policy makers should assign priority rights to vulnerable groups in future psychiatric planning. Policy measures should focus on the mental health of post-COVID-19 patients who seem to be particularly vulnerable.
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| format | Article |
| id | doaj-art-1905fcd9717f4a768f303acf7771c43d |
| institution | Kabale University |
| issn | 1392-0138 2029-4174 |
| language | English |
| publishDate | 2023-10-01 |
| publisher | Vilnius University Press |
| record_format | Article |
| series | Acta Medica Lituanica |
| spelling | doaj-art-1905fcd9717f4a768f303acf7771c43d2025-01-20T18:08:07ZengVilnius University PressActa Medica Lituanica1392-01382029-41742023-10-0130210.15388/Amed.2023.30.2.6Post-COVID-19 Syndrome and Related Dysautonomia: Reduced Quality of Life, Increased Anxiety and Manifestation of Depressive Symptoms: Evidence from GreecePetros Galanis0Aglaia Katsiroumpa1https://orcid.org/0000-0002-0920-6940Irene Vraka2Katerina Kosiara3Olga Siskou4Olympia Konstantakopoulou5Theodoros Katsoulas6https://orcid.org/0000-0001-8115-0462Parisis Gallos7Daphne Kaitelidou8Clinical Epidemiology Laboratory, Faculty of Nursing, National and Kapodistrian University of Athens, Athens, GreeceClinical Epidemiology Laboratory, Faculty of Nursing, National and Kapodistrian University of Athens, Athens, GreeceDepartment of Radiology, P. & A. Kyriakou Children’s Hospital, Athens, GreeceClinical Epidemiology Laboratory, Faculty of Nursing, National and Kapodistrian University of Athens, Athens, GreeceDepartment of Tourism Studies, University of Piraeus, Piraeus, GreeceCenter for Health Services Management and Evaluation, Faculty of Nursing, National and Kapodistrian University of Athens, Athens, GreeceFaculty of Nursing, National and Kapodistrian University of Athens, Athens, GreeceFaculty of Nursing, National and Kapodistrian University of Athens, Athens, GreeceCenter for Health Services Management and Evaluation, Faculty of Nursing, National and Kapodistrian University of Athens, Athens, Greece Background: Post-COVID-19 syndrome affects a significant number of SARS-CoV-2 infected individuals, even in asymptomatic cases causing several neurological and neuropsychiatric symptoms and signs. Materials and Methods: An online cross-sectional study with a convenience sample was conducted in Greece from November 2022 to January 2023. We measured the demographic and clinical characteristics of patients with post-COVID-19 dysautonomia in terms of the quality of life with the EQ-5D-3L, and anxiety and depressive symptoms by employing Patient Health Questionnaire-4. Results: The study population included 122 patients with post-COVID-19 syndrome. One out of four patients (27.8%) manifested post-COVID-19 dysautonomia, while the mean duration of COVID-19 symptoms was 11.6 months. Anxiety and depressive symptoms were worse after the post-COVID-19 syndrome (p<0.001 in both cases). A statistically significant reduction in quality of life was observed among patients after the post-COVID-19 syndrome (p<0.001 for both EQ-5D-3L index value and EQ-5D-3L VAS). Post-COVID-19 dysautonomia increased depression symptoms after developing the post-COVID-19 syndrome (p=0.02). We found a negative relationship between the duration of COVID-19 symptoms and the quality of life (p<0.001). Moreover, our results showed that depressive symptoms were more common among females after the post-COVID-19 syndrome (p=0.01). Also, the quality of life was lower among females than males (p=0.004 for EQ-5D-3L index value, and p=0.007 for EQ-5D-3L VAS). Conclusions: Our results suggest that post-COVID-19 syndrome causes a tremendous impact on the patients’ quality of life and mental health. In addition, we found that the groups most psychologically affected were patients with post-COVID-19 dysautonomia, females, and patients with a longer duration of symptoms. Policy makers should assign priority rights to vulnerable groups in future psychiatric planning. Policy measures should focus on the mental health of post-COVID-19 patients who seem to be particularly vulnerable. https://www.journals.vu.lt/AML/article/view/31683post-COVID-19 syndromedysautonomiaanxietydepressionquality of life |
| spellingShingle | Petros Galanis Aglaia Katsiroumpa Irene Vraka Katerina Kosiara Olga Siskou Olympia Konstantakopoulou Theodoros Katsoulas Parisis Gallos Daphne Kaitelidou Post-COVID-19 Syndrome and Related Dysautonomia: Reduced Quality of Life, Increased Anxiety and Manifestation of Depressive Symptoms: Evidence from Greece Acta Medica Lituanica post-COVID-19 syndrome dysautonomia anxiety depression quality of life |
| title | Post-COVID-19 Syndrome and Related Dysautonomia: Reduced Quality of Life, Increased Anxiety and Manifestation of Depressive Symptoms: Evidence from Greece |
| title_full | Post-COVID-19 Syndrome and Related Dysautonomia: Reduced Quality of Life, Increased Anxiety and Manifestation of Depressive Symptoms: Evidence from Greece |
| title_fullStr | Post-COVID-19 Syndrome and Related Dysautonomia: Reduced Quality of Life, Increased Anxiety and Manifestation of Depressive Symptoms: Evidence from Greece |
| title_full_unstemmed | Post-COVID-19 Syndrome and Related Dysautonomia: Reduced Quality of Life, Increased Anxiety and Manifestation of Depressive Symptoms: Evidence from Greece |
| title_short | Post-COVID-19 Syndrome and Related Dysautonomia: Reduced Quality of Life, Increased Anxiety and Manifestation of Depressive Symptoms: Evidence from Greece |
| title_sort | post covid 19 syndrome and related dysautonomia reduced quality of life increased anxiety and manifestation of depressive symptoms evidence from greece |
| topic | post-COVID-19 syndrome dysautonomia anxiety depression quality of life |
| url | https://www.journals.vu.lt/AML/article/view/31683 |
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