Deep learning approach based on a patch residual for pediatric supracondylar subtle fracture detection
Supracondylar humerus fractures in children are among the most common elbow fractures in pediatrics. However, their diagnosis can be particularly challenging due to the anatomical characteristics and imaging features of the pediatric skeleton. In recent years, convolutional neural networks (CNNs) ha...
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Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina
2025-01-01
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| Series: | Biomolecules & Biomedicine |
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| Online Access: | https://www.bjbms.org/ojs/index.php/bjbms/article/view/11341 |
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| author | Qingming Ye Zhilu Wang Yi Lou Yang Yang Jue Hou Zheng Liu Weiguang Liu Jiayu Li |
| author_facet | Qingming Ye Zhilu Wang Yi Lou Yang Yang Jue Hou Zheng Liu Weiguang Liu Jiayu Li |
| author_sort | Qingming Ye |
| collection | DOAJ |
| description | Supracondylar humerus fractures in children are among the most common elbow fractures in pediatrics. However, their diagnosis can be particularly challenging due to the anatomical characteristics and imaging features of the pediatric skeleton. In recent years, convolutional neural networks (CNNs) have achieved notable success in medical image analysis, though their performance typically relies on large-scale, high-quality labeled datasets. Unfortunately, labeled samples for pediatric supracondylar fractures are scarce and difficult to obtain. To address this issue, this paper introduces a deep learning-based multiscale patch residual network (MPR) for the automatic detection and localization of subtle pediatric supracondylar fractures. The MPR framework combines a CNN for automatic feature extraction with a multiscale generative adversarial network (GAN) to model skeletal integrity using healthy samples. By leveraging healthy images to learn the normal skeletal distribution, the approach reduces the dependency on labeled fracture data and effectively addresses the challenges posed by limited pediatric datasets. Datasets from two different hospitals were used, with data augmentation techniques applied during both training and validation. On an independent test set, the proposed model achieves an accuracy of 90.5%, with 89% sensitivity, 92% specificity, and an F1 score of 0.906—outperforming the diagnostic accuracy of emergency medicine physicians and approaching that of pediatric radiologists. Furthermore, the model demonstrates a fast inference speed of 1.1 seconds per sheet, underscoring its substantial potential for clinical application.
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| format | Article |
| id | doaj-art-18f5d40935db4044b01926c882cc2bfa |
| institution | DOAJ |
| issn | 2831-0896 2831-090X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina |
| record_format | Article |
| series | Biomolecules & Biomedicine |
| spelling | doaj-art-18f5d40935db4044b01926c882cc2bfa2025-08-20T02:41:21ZengAssociation of Basic Medical Sciences of Federation of Bosnia and HerzegovinaBiomolecules & Biomedicine2831-08962831-090X2025-01-0110.17305/bb.2024.11341Deep learning approach based on a patch residual for pediatric supracondylar subtle fracture detectionQingming Ye0https://orcid.org/0009-0004-7745-9757Zhilu Wang1Yi Lou2Yang Yang3Jue Hou4Zheng Liu5Weiguang Liu6Jiayu Li7Zhejiang Sci-Tech University, Hangzhou, ChinaZhejiang Sci-Tech University, Hangzhou, ChinaHangzhou Children's Hospital, Hangzhou, China Zhejiang Sci-Tech University, Hangzhou, ChinaZhejiang Sci-Tech University, Hangzhou, ChinaZhejiang Sci-Tech University, Hangzhou, ChinaHangzhou Children's Hospital, Hangzhou, China First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, ChinaSupracondylar humerus fractures in children are among the most common elbow fractures in pediatrics. However, their diagnosis can be particularly challenging due to the anatomical characteristics and imaging features of the pediatric skeleton. In recent years, convolutional neural networks (CNNs) have achieved notable success in medical image analysis, though their performance typically relies on large-scale, high-quality labeled datasets. Unfortunately, labeled samples for pediatric supracondylar fractures are scarce and difficult to obtain. To address this issue, this paper introduces a deep learning-based multiscale patch residual network (MPR) for the automatic detection and localization of subtle pediatric supracondylar fractures. The MPR framework combines a CNN for automatic feature extraction with a multiscale generative adversarial network (GAN) to model skeletal integrity using healthy samples. By leveraging healthy images to learn the normal skeletal distribution, the approach reduces the dependency on labeled fracture data and effectively addresses the challenges posed by limited pediatric datasets. Datasets from two different hospitals were used, with data augmentation techniques applied during both training and validation. On an independent test set, the proposed model achieves an accuracy of 90.5%, with 89% sensitivity, 92% specificity, and an F1 score of 0.906—outperforming the diagnostic accuracy of emergency medicine physicians and approaching that of pediatric radiologists. Furthermore, the model demonstrates a fast inference speed of 1.1 seconds per sheet, underscoring its substantial potential for clinical application. https://www.bjbms.org/ojs/index.php/bjbms/article/view/11341Deep learningpediatric supracondylar subtle fracturefracture detectionsmall data |
| spellingShingle | Qingming Ye Zhilu Wang Yi Lou Yang Yang Jue Hou Zheng Liu Weiguang Liu Jiayu Li Deep learning approach based on a patch residual for pediatric supracondylar subtle fracture detection Biomolecules & Biomedicine Deep learning pediatric supracondylar subtle fracture fracture detection small data |
| title | Deep learning approach based on a patch residual for pediatric supracondylar subtle fracture detection |
| title_full | Deep learning approach based on a patch residual for pediatric supracondylar subtle fracture detection |
| title_fullStr | Deep learning approach based on a patch residual for pediatric supracondylar subtle fracture detection |
| title_full_unstemmed | Deep learning approach based on a patch residual for pediatric supracondylar subtle fracture detection |
| title_short | Deep learning approach based on a patch residual for pediatric supracondylar subtle fracture detection |
| title_sort | deep learning approach based on a patch residual for pediatric supracondylar subtle fracture detection |
| topic | Deep learning pediatric supracondylar subtle fracture fracture detection small data |
| url | https://www.bjbms.org/ojs/index.php/bjbms/article/view/11341 |
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