Recurrent SARS-CoV-2 infections and their potential risk to public health - a systematic review.
<h4>Objective</h4>To inform quarantine and contact-tracing policies concerning re-positive cases-cases testing positive among those recovered.<h4>Materials and methods</h4>We systematically reviewed and appraised relevant literature from PubMed and Embase for the extent of re...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2021-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261221&type=printable |
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| Summary: | <h4>Objective</h4>To inform quarantine and contact-tracing policies concerning re-positive cases-cases testing positive among those recovered.<h4>Materials and methods</h4>We systematically reviewed and appraised relevant literature from PubMed and Embase for the extent of re-positive cases and their epidemiological characteristics.<h4>Results</h4>In 90 case reports/series, a total of 276 re-positive cases were found. Among confirmed reinfections, 50% occurred within 90 days from recovery. Four reports related onward transmission. In thirty-five observational studies, rate of re-positives ranged from zero to 50% with no onward transmissions reported. In eight reviews, pooled recurrence rate ranged from 12% to 17.7%. Probability of re-positive increased with several factors.<h4>Conclusion</h4>Recurrence of a positive SARS-CoV-2 test is commonly reported within the first weeks following recovery from a first infection. |
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| ISSN: | 1932-6203 |