The role of opportunistic pathogens as etiological agents of intrauterine infections
The study showed a high prevalence of markers of herpesvirus infections among mothers — from 71% to 98% of HSV, EBV and CMV infections and from 29% to 58% of HHV-6 infection. HSV remains the most common etiological agent of intrauterine infections among herpesviruses — markers of active infection ca...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
LLC "Diagnostics and Vaccines"
2019-10-01
|
| Series: | Детские инфекции (Москва) |
| Subjects: | |
| Online Access: | https://detinf.elpub.ru/jour/article/view/439 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849709289650782208 |
|---|---|
| author | V. V. Kosenchuk T. N. Rybalkina R. E. Boshyan N. V. Karazhas M. N. Kornienko P. A. Veselovsky M. Yu. Lysenkova M. S. Savenkova M. Yu. Ivanova |
| author_facet | V. V. Kosenchuk T. N. Rybalkina R. E. Boshyan N. V. Karazhas M. N. Kornienko P. A. Veselovsky M. Yu. Lysenkova M. S. Savenkova M. Yu. Ivanova |
| author_sort | V. V. Kosenchuk |
| collection | DOAJ |
| description | The study showed a high prevalence of markers of herpesvirus infections among mothers — from 71% to 98% of HSV, EBV and CMV infections and from 29% to 58% of HHV-6 infection. HSV remains the most common etiological agent of intrauterine infections among herpesviruses — markers of active infection caused by this virus were found in 28.3% samples. The difficulty of determining the source of infection in the absence of data in the early stages of pregnancy is presented on 4 out of 10 cases of active HHV-6 infection. Markers of active pneumocystic infection were detected only in mothers: in the group with children under the age of 21 days — in 21—27% of cases, with children aged 22 to 28 days — in 15—21%. In addition to non-specific multiple organ failure during intrauterine infections (26.3%), only one organ system was observed: hypoxic-hemorrhagic lesions of the central nervous system were diagnosed more often — 17%, as well as meningitis/encephalitis, or hepatitis, or pneumonia, or disorders of hematopoiesis, or rash. In 17.5% of children from the comparison group, i.e. without any clinical manifestations of intrauterine infections, markers of active herpes virus infections were detected. |
| format | Article |
| id | doaj-art-18efb077dbb84cd69819efbe2d37c966 |
| institution | DOAJ |
| issn | 2072-8107 |
| language | Russian |
| publishDate | 2019-10-01 |
| publisher | LLC "Diagnostics and Vaccines" |
| record_format | Article |
| series | Детские инфекции (Москва) |
| spelling | doaj-art-18efb077dbb84cd69819efbe2d37c9662025-08-20T03:15:20ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072019-10-01183172410.22627/2072-8107-2019-18-3-17-24404The role of opportunistic pathogens as etiological agents of intrauterine infectionsV. V. Kosenchuk0T. N. Rybalkina1R. E. Boshyan2N. V. Karazhas3M. N. Kornienko4P. A. Veselovsky5M. Yu. Lysenkova6M. S. Savenkova7M. Yu. Ivanova8N. F. Gamaleya Federal Research Center for Epidemiology and Microbiology, Ministry of Health of Russia; I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaN. F. Gamaleya Federal Research Center for Epidemiology and Microbiology, Ministry of Health of RussiaN. F. Gamaleya Federal Research Center for Epidemiology and Microbiology, Ministry of Health of Russia; I. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaN. F. Gamaleya Federal Research Center for Epidemiology and Microbiology, Ministry of Health of RussiaN. F. Gamaleya Federal Research Center for Epidemiology and Microbiology, Ministry of Health of RussiaN. F. Gamaleya Federal Research Center for Epidemiology and Microbiology, Ministry of Health of RussiaN. F. Gamaleya Federal Research Center for Epidemiology and Microbiology, Ministry of Health of RussiaN. I. Pirogov Russian National Research Medical University of the Ministry of Health of RussiaI. M. Sechenov First Moscow State Medical University (Sechenov University), Ministry of Health of RussiaThe study showed a high prevalence of markers of herpesvirus infections among mothers — from 71% to 98% of HSV, EBV and CMV infections and from 29% to 58% of HHV-6 infection. HSV remains the most common etiological agent of intrauterine infections among herpesviruses — markers of active infection caused by this virus were found in 28.3% samples. The difficulty of determining the source of infection in the absence of data in the early stages of pregnancy is presented on 4 out of 10 cases of active HHV-6 infection. Markers of active pneumocystic infection were detected only in mothers: in the group with children under the age of 21 days — in 21—27% of cases, with children aged 22 to 28 days — in 15—21%. In addition to non-specific multiple organ failure during intrauterine infections (26.3%), only one organ system was observed: hypoxic-hemorrhagic lesions of the central nervous system were diagnosed more often — 17%, as well as meningitis/encephalitis, or hepatitis, or pneumonia, or disorders of hematopoiesis, or rash. In 17.5% of children from the comparison group, i.e. without any clinical manifestations of intrauterine infections, markers of active herpes virus infections were detected.https://detinf.elpub.ru/jour/article/view/439intrauterine infectionsopportunistic infectionspathology of pregnancyherpesvirusespneumocystis |
| spellingShingle | V. V. Kosenchuk T. N. Rybalkina R. E. Boshyan N. V. Karazhas M. N. Kornienko P. A. Veselovsky M. Yu. Lysenkova M. S. Savenkova M. Yu. Ivanova The role of opportunistic pathogens as etiological agents of intrauterine infections Детские инфекции (Москва) intrauterine infections opportunistic infections pathology of pregnancy herpesviruses pneumocystis |
| title | The role of opportunistic pathogens as etiological agents of intrauterine infections |
| title_full | The role of opportunistic pathogens as etiological agents of intrauterine infections |
| title_fullStr | The role of opportunistic pathogens as etiological agents of intrauterine infections |
| title_full_unstemmed | The role of opportunistic pathogens as etiological agents of intrauterine infections |
| title_short | The role of opportunistic pathogens as etiological agents of intrauterine infections |
| title_sort | role of opportunistic pathogens as etiological agents of intrauterine infections |
| topic | intrauterine infections opportunistic infections pathology of pregnancy herpesviruses pneumocystis |
| url | https://detinf.elpub.ru/jour/article/view/439 |
| work_keys_str_mv | AT vvkosenchuk theroleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT tnrybalkina theroleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT reboshyan theroleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT nvkarazhas theroleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT mnkornienko theroleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT paveselovsky theroleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT myulysenkova theroleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT mssavenkova theroleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT myuivanova theroleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT vvkosenchuk roleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT tnrybalkina roleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT reboshyan roleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT nvkarazhas roleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT mnkornienko roleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT paveselovsky roleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT myulysenkova roleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT mssavenkova roleofopportunisticpathogensasetiologicalagentsofintrauterineinfections AT myuivanova roleofopportunisticpathogensasetiologicalagentsofintrauterineinfections |