Contrast-induced nephropathy - prevention and treatment
Introduction and purpose: Contrast-induced nephropathy (CIN) is kidney damage that can occur after the administration of contrast agents used in medical imaging procedures like angiography and CT scans. The exact mechanism is not fully understood but is believed to involve direct toxic effects, cha...
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Nicolaus Copernicus University in Toruń
2024-11-01
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| Series: | Quality in Sport |
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| Online Access: | https://apcz.umk.pl/QS/article/view/56249 |
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| author | Mateusz Bajak Julia Słowik Daniel Zapasek Michał Szczepański Maciej Mamczur Dominik Maciej Feret Jadwiga Inglot Julia Inglot Marcin Kuliga Damian Sowa Katarzyna Widawska |
| author_facet | Mateusz Bajak Julia Słowik Daniel Zapasek Michał Szczepański Maciej Mamczur Dominik Maciej Feret Jadwiga Inglot Julia Inglot Marcin Kuliga Damian Sowa Katarzyna Widawska |
| author_sort | Mateusz Bajak |
| collection | DOAJ |
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Introduction and purpose: Contrast-induced nephropathy (CIN) is kidney damage that can occur after the administration of contrast agents used in medical imaging procedures like angiography and CT scans. The exact mechanism is not fully understood but is believed to involve direct toxic effects, changes in kidney blood flow, and inflammation. Diagnosis is based on increased serum creatinine levels after contrast exposure. CIN poses challenges due to the rising use of contrast imaging, an aging population, and the increasing prevalence of chronic conditions like diabetes and hypertension. The Aim of this article is to summarize information on how to prevent contrast-induced nephropathy. Review of medications and pre-procedural screening and monitoring helpful to lower risk of CIN.
State of knowledge: Contrast-induced nephropathy (CIN) is a form of kidney damage that may occur following the administration of contrast agents used in medical imaging procedures. The exact mechanism of contrast-induced nephropathy is not fully understood, but it is believed to involve a combination of factors, including the direct toxic effects of the contrast agent on kidney cells, changes in blood flow to the kidneys, and the body's inflammatory response, direct effect of oxygen free radicals. The diagnosis of CIN is typically based on an increase in serum creatinine levels within a certain time frame after the administration of the contrast agent. According to European guidelines, the definition of CIN is increased creatinine level in serum by 25% from baseline or creatinine total level in serum increased by 0.5 mg/dL (44 µmol/L) 48-72h after contrast media administration.
Material and methods. A review of the available literature of PubMed database from 1992 – 2024.
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| format | Article |
| id | doaj-art-18ee322b54fb48d99202d2079f35d891 |
| institution | OA Journals |
| issn | 2450-3118 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Nicolaus Copernicus University in Toruń |
| record_format | Article |
| series | Quality in Sport |
| spelling | doaj-art-18ee322b54fb48d99202d2079f35d8912025-08-20T02:23:05ZengNicolaus Copernicus University in ToruńQuality in Sport2450-31182024-11-013410.12775/QS.2024.34.56249Contrast-induced nephropathy - prevention and treatmentMateusz Bajak0Julia Słowik1Daniel Zapasek2Michał Szczepański3Maciej Mamczur4Dominik Maciej Feret5Jadwiga Inglot6Julia Inglot7Marcin Kuliga8Damian Sowa9Katarzyna Widawska10Uniwersytecki Szpital Kliniczny w Rzeszowie: Rzeszów, podkarpackie, PLUniversity Teaching Hospital them F. Chopin in Rzeszów, Poland Fryderyka Szopena 2, 35-055 Rzeszów, PolandMedical Center in Łańcut, Poland Ignacego Paderewskiego 5, 37-100 Łańcut, PolandMedical Center in Łańcut, Poland Ignacego Paderewskiego 5, 37-100 Łańcut, PolandMedical Center in Łańcut, Poland Ignacego Paderewskiego 5, 37-100 Łańcut, PolandIndependent Public Health Care Complex No. 1 in Rzeszów, ul.Czackiego 3, 35-051 Rzeszów, PolandClinical Provincial Hospital No. 2 in Rzeszow, Poland Lwowska 60, 35-301 Rzeszów, PolandClinical Provincial Hospital No. 2 in Rzeszów, Poland Lwowska 60, 35-301 Rzeszów, PolandCollege of Medical Sciences, University of Rzeszów, Poland al. Tadeusza Rejtana 16C, 35-310 RzeszówClinical Provincial Hospital No. 2 in Rzeszow, Poland Lwowska 60, 35-301 Rzeszów, PolandPolish Red Cross Maritime Hospital in Gdynia, Poland Powstania Styczniowego 1, 81-519 Gdynia, Poland Introduction and purpose: Contrast-induced nephropathy (CIN) is kidney damage that can occur after the administration of contrast agents used in medical imaging procedures like angiography and CT scans. The exact mechanism is not fully understood but is believed to involve direct toxic effects, changes in kidney blood flow, and inflammation. Diagnosis is based on increased serum creatinine levels after contrast exposure. CIN poses challenges due to the rising use of contrast imaging, an aging population, and the increasing prevalence of chronic conditions like diabetes and hypertension. The Aim of this article is to summarize information on how to prevent contrast-induced nephropathy. Review of medications and pre-procedural screening and monitoring helpful to lower risk of CIN. State of knowledge: Contrast-induced nephropathy (CIN) is a form of kidney damage that may occur following the administration of contrast agents used in medical imaging procedures. The exact mechanism of contrast-induced nephropathy is not fully understood, but it is believed to involve a combination of factors, including the direct toxic effects of the contrast agent on kidney cells, changes in blood flow to the kidneys, and the body's inflammatory response, direct effect of oxygen free radicals. The diagnosis of CIN is typically based on an increase in serum creatinine levels within a certain time frame after the administration of the contrast agent. According to European guidelines, the definition of CIN is increased creatinine level in serum by 25% from baseline or creatinine total level in serum increased by 0.5 mg/dL (44 µmol/L) 48-72h after contrast media administration. Material and methods. A review of the available literature of PubMed database from 1992 – 2024. https://apcz.umk.pl/QS/article/view/56249Contrast-induced nephropathyradiologyacute kidney injuryiodineradioiodinecontrast media |
| spellingShingle | Mateusz Bajak Julia Słowik Daniel Zapasek Michał Szczepański Maciej Mamczur Dominik Maciej Feret Jadwiga Inglot Julia Inglot Marcin Kuliga Damian Sowa Katarzyna Widawska Contrast-induced nephropathy - prevention and treatment Quality in Sport Contrast-induced nephropathy radiology acute kidney injury iodine radioiodine contrast media |
| title | Contrast-induced nephropathy - prevention and treatment |
| title_full | Contrast-induced nephropathy - prevention and treatment |
| title_fullStr | Contrast-induced nephropathy - prevention and treatment |
| title_full_unstemmed | Contrast-induced nephropathy - prevention and treatment |
| title_short | Contrast-induced nephropathy - prevention and treatment |
| title_sort | contrast induced nephropathy prevention and treatment |
| topic | Contrast-induced nephropathy radiology acute kidney injury iodine radioiodine contrast media |
| url | https://apcz.umk.pl/QS/article/view/56249 |
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