Lactoferrin alleviates the adverse effects of early-life inflammation on depression in adults by regulating the activation of microglia

Lactoferrin alleviates the adverse effects of early-life inflammation on depression in adults by regulating the activation of microglia

Abstract Lactation is a crucial phase of brain development, and the events and nutrients during this period have long-term consequences for the occurrence of depression. This study investigated the effect and mechanism of lactoferrin (LF) deficiency during lactation on depression in adulthood. Lacta...

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Bibliographic Details
Main Authors: Wenli Wang, Qin An, Yunxia Zou, Yunping Dai, Qingyong Meng, Yali Zhang
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Molecular Medicine
Subjects:
Lactation
Lactoferrin
Inflammation
Depression
Innate immunity
Microglia
Online Access:https://doi.org/10.1186/s10020-025-01094-9
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