A Possible Link between Infection with Burkholderia Bacteria and Systemic Lupus Erythematosus Based on Epitope Mimicry

We previously demonstrated that purified polyclonal and monoclonal anti-dsDNA antibodies bind a 15-mer peptide ASPVTARVLWKASHV in ELISA and Dot blot. This 15-mer peptide partial sequence ARVLWKASH shares similarity with burkholderia bacterial cytochrome B 561 partial sequence ARVLWRATH. In this stud...

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Bibliographic Details
Main Authors: Wei Zhang, Morris Reichlin
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2008/683489
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