Chronic myeloid leukemia in childhood: a case report

Chronic myeloid leukemia is a rare hematological malignancy in the pediatric age group. It is a clonal hematopoietic stem cell disorder in which granulocytes are the major proliferative components with the presence of the BCR-ABL1 fusion gene. Here, we report a case of CML in a three - year child wi...

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Main Authors: Uma Bhatta, Dosti Regmi
Format: Article
Language:English
Published: Association of Clinical Pathologists of Nepal 2021-09-01
Series:Journal of Pathology of Nepal
Subjects:
Online Access:https://www.nepjol.info/index.php/JPN/article/view/35291
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author Uma Bhatta
Dosti Regmi
author_facet Uma Bhatta
Dosti Regmi
author_sort Uma Bhatta
collection DOAJ
description Chronic myeloid leukemia is a rare hematological malignancy in the pediatric age group. It is a clonal hematopoietic stem cell disorder in which granulocytes are the major proliferative components with the presence of the BCR-ABL1 fusion gene. Here, we report a case of CML in a three - year child with a clinical presentation of fever and abdominal distension. The diagnosis was made based on bone marrow aspiration findings and molecular study.
format Article
id doaj-art-18e84feabdcc4e9eabe41096e4377a88
institution Kabale University
issn 2091-0797
2091-0908
language English
publishDate 2021-09-01
publisher Association of Clinical Pathologists of Nepal
record_format Article
series Journal of Pathology of Nepal
spelling doaj-art-18e84feabdcc4e9eabe41096e4377a882025-08-21T07:13:24ZengAssociation of Clinical Pathologists of NepalJournal of Pathology of Nepal2091-07972091-09082021-09-011121873187510.3126/jpn.v11i2.3529132086Chronic myeloid leukemia in childhood: a case reportUma Bhatta0https://orcid.org/0000-0002-7033-858XDosti Regmi1Kanti Children’s Hospital, Kathmandu, NepalKanti Children’s Hospital, Kathmandu, NepalChronic myeloid leukemia is a rare hematological malignancy in the pediatric age group. It is a clonal hematopoietic stem cell disorder in which granulocytes are the major proliferative components with the presence of the BCR-ABL1 fusion gene. Here, we report a case of CML in a three - year child with a clinical presentation of fever and abdominal distension. The diagnosis was made based on bone marrow aspiration findings and molecular study.https://www.nepjol.info/index.php/JPN/article/view/35291bcr/abl1; chronic myeloid leukemia; juvenile myelomonocytic leukemia
spellingShingle Uma Bhatta
Dosti Regmi
Chronic myeloid leukemia in childhood: a case report
Journal of Pathology of Nepal
bcr/abl1; chronic myeloid leukemia; juvenile myelomonocytic leukemia
title Chronic myeloid leukemia in childhood: a case report
title_full Chronic myeloid leukemia in childhood: a case report
title_fullStr Chronic myeloid leukemia in childhood: a case report
title_full_unstemmed Chronic myeloid leukemia in childhood: a case report
title_short Chronic myeloid leukemia in childhood: a case report
title_sort chronic myeloid leukemia in childhood a case report
topic bcr/abl1; chronic myeloid leukemia; juvenile myelomonocytic leukemia
url https://www.nepjol.info/index.php/JPN/article/view/35291
work_keys_str_mv AT umabhatta chronicmyeloidleukemiainchildhoodacasereport
AT dostiregmi chronicmyeloidleukemiainchildhoodacasereport