Polymorphism of DNA repair genes XRCC1 280, XRCC1 194, XRCC1 339 and XPD 751 with stomach cancer
We evaluated the frequency distribution of polymorphic variants in DNA repair genes XRCC1 280, XRCC1 194, XRCC1 399 and XPD 751 gastric cancer patients and healthy controls, leading to new fundamental knowledge and molecular genetic markers of gastric cancer. Statistically significant differences we...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2011-12-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/1498 |
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| author | S. S. Rakitin A. I. Dmitriyeva V. V. Novitsky I. A. Kuznetsova B. A. Avkhimenko |
| author_facet | S. S. Rakitin A. I. Dmitriyeva V. V. Novitsky I. A. Kuznetsova B. A. Avkhimenko |
| author_sort | S. S. Rakitin |
| collection | DOAJ |
| description | We evaluated the frequency distribution of polymorphic variants in DNA repair genes XRCC1 280, XRCC1 194, XRCC1 399 and XPD 751 gastric cancer patients and healthy controls, leading to new fundamental knowledge and molecular genetic markers of gastric cancer. Statistically significant differences were identified in the two groups for the three excision repair gene XRCC1 280, XRCC1 399 and XPD 751, relative risks were calculated of gastric cancer in carriers of the minor variants of these genes. |
| format | Article |
| id | doaj-art-18e7a3127cb349bdaf6e8f391e6ed52f |
| institution | DOAJ |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2011-12-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-18e7a3127cb349bdaf6e8f391e6ed52f2025-08-20T03:21:44ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842011-12-01106353910.20538/1682-0363-2011-6-35-391004Polymorphism of DNA repair genes XRCC1 280, XRCC1 194, XRCC1 339 and XPD 751 with stomach cancerS. S. Rakitin0A. I. Dmitriyeva1V. V. Novitsky2I. A. Kuznetsova3B. A. Avkhimenko4Сибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетОГУЗ «Томский областной онкологический диспансер»We evaluated the frequency distribution of polymorphic variants in DNA repair genes XRCC1 280, XRCC1 194, XRCC1 399 and XPD 751 gastric cancer patients and healthy controls, leading to new fundamental knowledge and molecular genetic markers of gastric cancer. Statistically significant differences were identified in the two groups for the three excision repair gene XRCC1 280, XRCC1 399 and XPD 751, relative risks were calculated of gastric cancer in carriers of the minor variants of these genes.https://bulletin.ssmu.ru/jour/article/view/1498gastric cancerdna repairpolymorphismoddis ratiogastric cancerogenesis |
| spellingShingle | S. S. Rakitin A. I. Dmitriyeva V. V. Novitsky I. A. Kuznetsova B. A. Avkhimenko Polymorphism of DNA repair genes XRCC1 280, XRCC1 194, XRCC1 339 and XPD 751 with stomach cancer Бюллетень сибирской медицины gastric cancer dna repair polymorphism oddis ratiogastric cancerogenesis |
| title | Polymorphism of DNA repair genes XRCC1 280, XRCC1 194, XRCC1 339 and XPD 751 with stomach cancer |
| title_full | Polymorphism of DNA repair genes XRCC1 280, XRCC1 194, XRCC1 339 and XPD 751 with stomach cancer |
| title_fullStr | Polymorphism of DNA repair genes XRCC1 280, XRCC1 194, XRCC1 339 and XPD 751 with stomach cancer |
| title_full_unstemmed | Polymorphism of DNA repair genes XRCC1 280, XRCC1 194, XRCC1 339 and XPD 751 with stomach cancer |
| title_short | Polymorphism of DNA repair genes XRCC1 280, XRCC1 194, XRCC1 339 and XPD 751 with stomach cancer |
| title_sort | polymorphism of dna repair genes xrcc1 280 xrcc1 194 xrcc1 339 and xpd 751 with stomach cancer |
| topic | gastric cancer dna repair polymorphism oddis ratiogastric cancerogenesis |
| url | https://bulletin.ssmu.ru/jour/article/view/1498 |
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