Immunoinformatic approach to the design of a novel multi-epitope vaccine against Leishmania major fused to human IgG-Fc

Immunoinformatic approach to the design of a novel multi-epitope vaccine against Leishmania major fused to human IgG-Fc

Background and purpose: Cutaneous leishmaniasis poses significant health and socioeconomic challenges, making vaccine development a top priority, especially in endemic regions. Cysteine proteases, KMP-11, and HASPB proteins are promising candidates for leishmaniasis vaccine development owing to thei...

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Bibliographic Details
Main Authors: Mahmood Fadaie, Zabihollah Shahmoradi, Hossein Khanahmad
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Research in Pharmaceutical Sciences
Subjects:
adjuvant
igg-fc
immunodominant epitopes
leishmania major
subunit vaccine
Online Access:https://journals.lww.com/10.4103/RPS.RPS_145_24
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