Physician awareness and understanding of chronic inflammatory demyelinating polyradiculoneuropathy in Japan: a web-based study
Objectives To investigate potential knowledge gaps between neurologists and non-specialists and identify challenges in the current management of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), with a focus on ‘early diagnosis’ and ‘appropriate treatment’ for CIDP.Design A non-inter...
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| Format: | Article |
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BMJ Publishing Group
2024-03-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/14/3/e083669.full |
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| author | Yukio Takeshita Akinori Oh Yasuaki Imajo Masayoshi Kikutani Nobuaki Okamatsu |
| author_facet | Yukio Takeshita Akinori Oh Yasuaki Imajo Masayoshi Kikutani Nobuaki Okamatsu |
| author_sort | Yukio Takeshita |
| collection | DOAJ |
| description | Objectives To investigate potential knowledge gaps between neurologists and non-specialists and identify challenges in the current management of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), with a focus on ‘early diagnosis’ and ‘appropriate treatment’ for CIDP.Design A non-interventional, cross-sectional, web-based quantitative survey of physicians working in healthcare clinics or hospitals in Japan.Setting Participants were recruited from the Nikkei Business Publications panel from 18 August to 14 September 2022.Participants Responses from 360 physicians (120 each of internists, orthopaedists and neurologists) were collected.Outcome measures Responses relating to a CIDP hypothetical case and current understanding were assessed to determine awareness, collaboration preferences and diagnosis and treatment decisions.Results Understanding of CIDP was 90.8% among neurologists, 10.8% among orthopaedists and 13.3% among internists; >80% of orthopaedists and internists answered that neurologists are preferable for treatment. Diagnostic assessment using a hypothetical case showed 95.0% of neurologists, 74.2% of orthopaedists and 72.5% of internists suspected CIDP. Among orthopaedists and internists suspecting CIDP, >70% considered referring to neurology, while ~10% considered continuing treatment without a referral. Among neurologists, 69.4% chose intravenous immunoglobulin (IVIg) as first-line treatment and determined effectiveness to be ≤3 months.Conclusions Orthopaedists and internists had lower CIDP awareness compared with neurologists, which may lead to inadequate referrals to neurology. Evaluation of IVIg effectiveness for maintenance therapy occurred earlier than the guideline recommendations (6–12 months), risking premature discontinuation. Improving CIDP knowledge among orthopaedists and internists is critical for better diagnosis and collaboration with neurologists. Neurologists should consider slow and careful evaluation of IVIg maintenance therapy.Trial registration number UMIN000048516. |
| format | Article |
| id | doaj-art-18e1051d904540c79b5af96a0310e42e |
| institution | OA Journals |
| issn | 2044-6055 |
| language | English |
| publishDate | 2024-03-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-18e1051d904540c79b5af96a0310e42e2025-08-20T02:13:52ZengBMJ Publishing GroupBMJ Open2044-60552024-03-0114310.1136/bmjopen-2023-083669Physician awareness and understanding of chronic inflammatory demyelinating polyradiculoneuropathy in Japan: a web-based studyYukio Takeshita0Akinori Oh1Yasuaki Imajo2Masayoshi Kikutani3Nobuaki Okamatsu4Department of Neurotherapeutics/Neurology and Clinical Neuroscience, Yamaguchi University Graduate School of Medicine, Yamaguchi, JapanJapan Medical Office, Takeda Pharmaceutical Company Limited, Tokyo, JapanDepartment of Orthopedic Surgery, Japan Community Health Care Organization Tokuyama Central Hospital, Yamaguchi, JapanJapan Medical Office, Takeda Pharmaceutical Company Limited, Tokyo, JapanJapan Medical Office, Takeda Pharmaceutical Company Limited, Tokyo, JapanObjectives To investigate potential knowledge gaps between neurologists and non-specialists and identify challenges in the current management of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), with a focus on ‘early diagnosis’ and ‘appropriate treatment’ for CIDP.Design A non-interventional, cross-sectional, web-based quantitative survey of physicians working in healthcare clinics or hospitals in Japan.Setting Participants were recruited from the Nikkei Business Publications panel from 18 August to 14 September 2022.Participants Responses from 360 physicians (120 each of internists, orthopaedists and neurologists) were collected.Outcome measures Responses relating to a CIDP hypothetical case and current understanding were assessed to determine awareness, collaboration preferences and diagnosis and treatment decisions.Results Understanding of CIDP was 90.8% among neurologists, 10.8% among orthopaedists and 13.3% among internists; >80% of orthopaedists and internists answered that neurologists are preferable for treatment. Diagnostic assessment using a hypothetical case showed 95.0% of neurologists, 74.2% of orthopaedists and 72.5% of internists suspected CIDP. Among orthopaedists and internists suspecting CIDP, >70% considered referring to neurology, while ~10% considered continuing treatment without a referral. Among neurologists, 69.4% chose intravenous immunoglobulin (IVIg) as first-line treatment and determined effectiveness to be ≤3 months.Conclusions Orthopaedists and internists had lower CIDP awareness compared with neurologists, which may lead to inadequate referrals to neurology. Evaluation of IVIg effectiveness for maintenance therapy occurred earlier than the guideline recommendations (6–12 months), risking premature discontinuation. Improving CIDP knowledge among orthopaedists and internists is critical for better diagnosis and collaboration with neurologists. Neurologists should consider slow and careful evaluation of IVIg maintenance therapy.Trial registration number UMIN000048516.https://bmjopen.bmj.com/content/14/3/e083669.full |
| spellingShingle | Yukio Takeshita Akinori Oh Yasuaki Imajo Masayoshi Kikutani Nobuaki Okamatsu Physician awareness and understanding of chronic inflammatory demyelinating polyradiculoneuropathy in Japan: a web-based study BMJ Open |
| title | Physician awareness and understanding of chronic inflammatory demyelinating polyradiculoneuropathy in Japan: a web-based study |
| title_full | Physician awareness and understanding of chronic inflammatory demyelinating polyradiculoneuropathy in Japan: a web-based study |
| title_fullStr | Physician awareness and understanding of chronic inflammatory demyelinating polyradiculoneuropathy in Japan: a web-based study |
| title_full_unstemmed | Physician awareness and understanding of chronic inflammatory demyelinating polyradiculoneuropathy in Japan: a web-based study |
| title_short | Physician awareness and understanding of chronic inflammatory demyelinating polyradiculoneuropathy in Japan: a web-based study |
| title_sort | physician awareness and understanding of chronic inflammatory demyelinating polyradiculoneuropathy in japan a web based study |
| url | https://bmjopen.bmj.com/content/14/3/e083669.full |
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