Psychometric properties and meaningful change thresholds for the QOL-E instrument in patients with myelodysplastic neoplasms

Psychometric properties and meaningful change thresholds for the QOL-E instrument in patients with myelodysplastic neoplasms

BackgroundMyelodysplastic neoplasms (MDS) are characterized by ineffective hematopoiesis, peripheral blood cytopenias, and an increased risk of progression to acute myeloid leukemia. One of the main treatment goals is improving quality of life (QoL), particularly for patients with lower-risk MDS (LR...

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Main Authors: Esther Natalie Oliva, Shien Guo, Jennifer Lord-Bessen, Aylin Yucel, Roberto Latagliata, Massimo Breccia, Giuseppe A. Palumbo, Grazia Sanpaolo, Marta Riva, Valeria Santini, Uwe Platzbecker, Guillermo Garcia-Manero, Pierre Fenaux, Christopher G. Pelligra
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Oncology
Subjects:
health-related quality of life
myelodysplastic syndromes
myelodysplastic neoplasms
patient-reported outcomes
psychometric analysis
QOL-E
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1507854/full
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