Effectiveness of Cognitive Behavioral Therapy on Multi-drug Resistant Tuberculosis Patients in Mongolia: 10 years experiences

Objective: During multidrug-resistant tuberculosis (MDR-TB) treatment, patients face de­pression and anxiety. This study aims to evaluate the effects of cognitive behavioral therapy (CBT) on the psychological status and risk of loss to follow-up (LTFU) during MDR-TB treat­ment in Mongolia. Method: E...

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Main Authors: Dorjmaa Dashdavaa, Bolor Rash, Ser-Od Khuyagaa, Anuzaya Purevdagva, Kyung Hyun Oh, Oyunsuren Davaasuren, Naranzul Dambaa, Baatarkhuu Oidov, Khishigsuren Zuunnast
Format: Article
Language:English
Published: Mongolian National University of Medical Sciences 2024-06-01
Series:Central Asian Journal of Medical Sciences
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Online Access:https://www.mongoliajol.info/index.php/CAJMS/article/view/3573
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author Dorjmaa Dashdavaa
Bolor Rash
Ser-Od Khuyagaa
Anuzaya Purevdagva
Kyung Hyun Oh
Oyunsuren Davaasuren
Naranzul Dambaa
Baatarkhuu Oidov
Khishigsuren Zuunnast
author_facet Dorjmaa Dashdavaa
Bolor Rash
Ser-Od Khuyagaa
Anuzaya Purevdagva
Kyung Hyun Oh
Oyunsuren Davaasuren
Naranzul Dambaa
Baatarkhuu Oidov
Khishigsuren Zuunnast
author_sort Dorjmaa Dashdavaa
collection DOAJ
description Objective: During multidrug-resistant tuberculosis (MDR-TB) treatment, patients face de­pression and anxiety. This study aims to evaluate the effects of cognitive behavioral therapy (CBT) on the psychological status and risk of loss to follow-up (LTFU) during MDR-TB treat­ment in Mongolia. Method: Eligible participants were randomly assigned to intervention and control groups. Intervention group participants underwent CBT, while control group par­ticipants received standard patient education. Psychological status was assessed before and after CBT. MDR-TB treatment outcomes were evaluated as internationally defined. Results: The study included a total of 83 patients. After CBT, depression and anxiety levels decreased by 12% and 16%, respectively, in the intervention group, whereas the control group showed a 4% decrease in depression and an 8.5% increase in anxiety levels. MDR-TB treatment outcomes revealed an 8% higher treatment success rate and a fivefold reduction in LTFU rate in the intervention group compared to the control group. In multivariable logistic regression, risk factors associated with increased LTFU were living alone (OR 12.7, p=0.031) and not being provided CBT (OR 16.1, p=0.040). Conclusion: Our study suggests that CBT not only alleviates these psychological challenges but also diminishes the risk of LTFU during treat­ment, leading to improved MDR-TB treatment success.
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institution Kabale University
issn 2413-8681
2414-9772
language English
publishDate 2024-06-01
publisher Mongolian National University of Medical Sciences
record_format Article
series Central Asian Journal of Medical Sciences
spelling doaj-art-18bfda6919de42949b0bdd1f7e118bf12025-08-20T03:25:26ZengMongolian National University of Medical SciencesCentral Asian Journal of Medical Sciences2413-86812414-97722024-06-01102475610.24079/cajms.2024.02.0023524Effectiveness of Cognitive Behavioral Therapy on Multi-drug Resistant Tuberculosis Patients in Mongolia: 10 years experiencesDorjmaa Dashdavaa0https://orcid.org/0000-0002-4776-3174Bolor Rash1Ser-Od Khuyagaa2Anuzaya Purevdagva3Kyung Hyun Oh4Oyunsuren Davaasuren5Naranzul Dambaa6Baatarkhuu Oidov7Khishigsuren Zuunnast8Department of Mental Health, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, MongoliaTuberculosis clinic, National Center for Communicable Diseases, Ulaanbaatar, MongoliaDepartment of Epidemiology and Biostatistics, School of Public Health, Mongolian National University of Medical Sciences, Ulaanbaatar, MongoliaDepartment of Communicable Diseases Control, World Health Organization, MongoliaDepartment of End TB, World Health Organization Regional Offi ce for the Western Pacifi c, PhilippinesDepartment of Mental Health, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, MongoliaTuberculosis Surveillance and Research Department, National Center for Communicable Diseases, Ulaanbaatar, MongoliaDepartment of Infectious Diseases, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, MongoliaDepartment of Mental Health, School of Medicine, Mongolian National University of Medical Sciences, Ulaanbaatar, MongoliaObjective: During multidrug-resistant tuberculosis (MDR-TB) treatment, patients face de­pression and anxiety. This study aims to evaluate the effects of cognitive behavioral therapy (CBT) on the psychological status and risk of loss to follow-up (LTFU) during MDR-TB treat­ment in Mongolia. Method: Eligible participants were randomly assigned to intervention and control groups. Intervention group participants underwent CBT, while control group par­ticipants received standard patient education. Psychological status was assessed before and after CBT. MDR-TB treatment outcomes were evaluated as internationally defined. Results: The study included a total of 83 patients. After CBT, depression and anxiety levels decreased by 12% and 16%, respectively, in the intervention group, whereas the control group showed a 4% decrease in depression and an 8.5% increase in anxiety levels. MDR-TB treatment outcomes revealed an 8% higher treatment success rate and a fivefold reduction in LTFU rate in the intervention group compared to the control group. In multivariable logistic regression, risk factors associated with increased LTFU were living alone (OR 12.7, p=0.031) and not being provided CBT (OR 16.1, p=0.040). Conclusion: Our study suggests that CBT not only alleviates these psychological challenges but also diminishes the risk of LTFU during treat­ment, leading to improved MDR-TB treatment success.https://www.mongoliajol.info/index.php/CAJMS/article/view/3573tuberculosisdepressionanxietymental healthpsychotherapy
spellingShingle Dorjmaa Dashdavaa
Bolor Rash
Ser-Od Khuyagaa
Anuzaya Purevdagva
Kyung Hyun Oh
Oyunsuren Davaasuren
Naranzul Dambaa
Baatarkhuu Oidov
Khishigsuren Zuunnast
Effectiveness of Cognitive Behavioral Therapy on Multi-drug Resistant Tuberculosis Patients in Mongolia: 10 years experiences
Central Asian Journal of Medical Sciences
tuberculosis
depression
anxiety
mental health
psychotherapy
title Effectiveness of Cognitive Behavioral Therapy on Multi-drug Resistant Tuberculosis Patients in Mongolia: 10 years experiences
title_full Effectiveness of Cognitive Behavioral Therapy on Multi-drug Resistant Tuberculosis Patients in Mongolia: 10 years experiences
title_fullStr Effectiveness of Cognitive Behavioral Therapy on Multi-drug Resistant Tuberculosis Patients in Mongolia: 10 years experiences
title_full_unstemmed Effectiveness of Cognitive Behavioral Therapy on Multi-drug Resistant Tuberculosis Patients in Mongolia: 10 years experiences
title_short Effectiveness of Cognitive Behavioral Therapy on Multi-drug Resistant Tuberculosis Patients in Mongolia: 10 years experiences
title_sort effectiveness of cognitive behavioral therapy on multi drug resistant tuberculosis patients in mongolia 10 years experiences
topic tuberculosis
depression
anxiety
mental health
psychotherapy
url https://www.mongoliajol.info/index.php/CAJMS/article/view/3573
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