Exploring associations between estrogen and gene candidates identified by coronary artery disease genome-wide association studies

Exploring associations between estrogen and gene candidates identified by coronary artery disease genome-wide association studies

IntroductionCoronary artery disease (CAD) is the leading cause of death around the world, with epidemiological sex and gender differences in prevalence, pathophysiology and outcomes. It has been hypothesized that sex steroids, like estrogen, may contribute to these sex differences. There is a relati...

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Bibliographic Details
Main Authors: Ava P. Aminbakhsh, Emilie T. Théberge, Elizabeth Burden, Cindy Kalenga Adejumo, Annabel K. Gravely, Anna Lehman, Tara L. Sedlak
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
coronary artery disease
genome wide association study
estrogen
gene candidates
sex differences
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2025.1502985/full
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