An open-source interactive AI framework for assisting automatic literature review in forensic medicine: Focus on brain injury mechanisms.

<h4>Background and objective</h4>Systematic reviews and meta-analyses are critical in forensic medicine; however, these processes are labor-intensive and time-consuming. ASReview, an open-source machine learning framework, has demonstrated potential to improve the efficiency and transpar...

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Main Authors: Ya-Wen Liu, Dong-Hua Zou, He-Wen Dong, Yuan-Yuan Liu, En-Hao Fu, Zhi-Ling Tian, Ning-Guo Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0329349
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author Ya-Wen Liu
Dong-Hua Zou
He-Wen Dong
Yuan-Yuan Liu
En-Hao Fu
Zhi-Ling Tian
Ning-Guo Liu
author_facet Ya-Wen Liu
Dong-Hua Zou
He-Wen Dong
Yuan-Yuan Liu
En-Hao Fu
Zhi-Ling Tian
Ning-Guo Liu
author_sort Ya-Wen Liu
collection DOAJ
description <h4>Background and objective</h4>Systematic reviews and meta-analyses are critical in forensic medicine; however, these processes are labor-intensive and time-consuming. ASReview, an open-source machine learning framework, has demonstrated potential to improve the efficiency and transparency of systematic reviews in other disciplines. Nevertheless, its applicability to forensic medicine remains unexplored. This study evaluates the utility of ASReview for forensic medical literature review.<h4>Methods</h4>A three-stage experimental design was implemented. First, stratified five-fold cross-validation was conducted to assess ASReview's compatibility with forensic medical literature. Second, incremental learning and sampling methods were employed to analyze the model's performance on imbalanced datasets and the effect of training set size on predictive accuracy. Third, gold standard were translated into computational languages to evaluate ASReview's capacity to address real-world systematic review objectives.<h4>Results</h4>ASReview exhibited robust viability for screening forensic medical literature. The tool efficiently prioritized relevant studies while excluding irrelevant records, thereby improving review productivity. Model performance remained stable when labeled training data constituted less than 80% of the total sample size. Notably, when the training set proportion ranged from 10% to 55%, ASReview's predictions aligned closely with human reviewer decisions.<h4>Conclusion</h4>ASReview represents a promising tool for forensic medical literature review. Its ability to handle imbalanced datasets and gather goal-oriented information enhances the efficiency and transparency of systematic reviews and meta-analyses in forensic medicine. Further research is required to optimize implementation strategies and validate its utility across diverse forensic medical contexts.
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spelling doaj-art-18b99bcffd174e52b599e2162c6e206a2025-08-20T03:39:14ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01208e032934910.1371/journal.pone.0329349An open-source interactive AI framework for assisting automatic literature review in forensic medicine: Focus on brain injury mechanisms.Ya-Wen LiuDong-Hua ZouHe-Wen DongYuan-Yuan LiuEn-Hao FuZhi-Ling TianNing-Guo Liu<h4>Background and objective</h4>Systematic reviews and meta-analyses are critical in forensic medicine; however, these processes are labor-intensive and time-consuming. ASReview, an open-source machine learning framework, has demonstrated potential to improve the efficiency and transparency of systematic reviews in other disciplines. Nevertheless, its applicability to forensic medicine remains unexplored. This study evaluates the utility of ASReview for forensic medical literature review.<h4>Methods</h4>A three-stage experimental design was implemented. First, stratified five-fold cross-validation was conducted to assess ASReview's compatibility with forensic medical literature. Second, incremental learning and sampling methods were employed to analyze the model's performance on imbalanced datasets and the effect of training set size on predictive accuracy. Third, gold standard were translated into computational languages to evaluate ASReview's capacity to address real-world systematic review objectives.<h4>Results</h4>ASReview exhibited robust viability for screening forensic medical literature. The tool efficiently prioritized relevant studies while excluding irrelevant records, thereby improving review productivity. Model performance remained stable when labeled training data constituted less than 80% of the total sample size. Notably, when the training set proportion ranged from 10% to 55%, ASReview's predictions aligned closely with human reviewer decisions.<h4>Conclusion</h4>ASReview represents a promising tool for forensic medical literature review. Its ability to handle imbalanced datasets and gather goal-oriented information enhances the efficiency and transparency of systematic reviews and meta-analyses in forensic medicine. Further research is required to optimize implementation strategies and validate its utility across diverse forensic medical contexts.https://doi.org/10.1371/journal.pone.0329349
spellingShingle Ya-Wen Liu
Dong-Hua Zou
He-Wen Dong
Yuan-Yuan Liu
En-Hao Fu
Zhi-Ling Tian
Ning-Guo Liu
An open-source interactive AI framework for assisting automatic literature review in forensic medicine: Focus on brain injury mechanisms.
PLoS ONE
title An open-source interactive AI framework for assisting automatic literature review in forensic medicine: Focus on brain injury mechanisms.
title_full An open-source interactive AI framework for assisting automatic literature review in forensic medicine: Focus on brain injury mechanisms.
title_fullStr An open-source interactive AI framework for assisting automatic literature review in forensic medicine: Focus on brain injury mechanisms.
title_full_unstemmed An open-source interactive AI framework for assisting automatic literature review in forensic medicine: Focus on brain injury mechanisms.
title_short An open-source interactive AI framework for assisting automatic literature review in forensic medicine: Focus on brain injury mechanisms.
title_sort open source interactive ai framework for assisting automatic literature review in forensic medicine focus on brain injury mechanisms
url https://doi.org/10.1371/journal.pone.0329349
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