Evaluation of a Non-Enzymatic Electrochemical Sensor Based on Co(OH)<sub>2</sub>-Functionalized Carbon Nanotubes for Glucose Detection
This work reports on the assessment of a non-hydrolytic electrochemical sensor for glucose sensing that is developed using functionalized carbon nanotubes (fCNTs)/Co(OH)<sub>2</sub>. The morphology of the nanocomposite was investigated by scanning electron microscopy, which revealed that...
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MDPI AG
2024-12-01
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| Online Access: | https://www.mdpi.com/1424-8220/24/23/7707 |
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| author | Diego Bolaños-Mendez Lenys Fernández Rafael Uribe Alisson Cunalata-Castro Gema González Isamara Rojas Andrés Chico-Proano Alexis Debut Luis Alberto Celi Patricio Espinoza-Montero |
| author_facet | Diego Bolaños-Mendez Lenys Fernández Rafael Uribe Alisson Cunalata-Castro Gema González Isamara Rojas Andrés Chico-Proano Alexis Debut Luis Alberto Celi Patricio Espinoza-Montero |
| author_sort | Diego Bolaños-Mendez |
| collection | DOAJ |
| description | This work reports on the assessment of a non-hydrolytic electrochemical sensor for glucose sensing that is developed using functionalized carbon nanotubes (fCNTs)/Co(OH)<sub>2</sub>. The morphology of the nanocomposite was investigated by scanning electron microscopy, which revealed that the CNTs interacted with Co(OH)<sub>2</sub>. This content formed a nanocomposite that improved the electrochemical characterizations of the electrode, including the electrochemical active surface area and capacitance, thus improving sensitivity to glucose. In the electrochemical characterization by cyclic voltammetry and chronoamperometry, the increase in catalytic activity by Co(OH)<sub>2</sub> improved the stability and reproducibility of the glucose sensor without the use of enzymes, and its concentration range was between 50 and 700 μmol L<sup>−1</sup>. The sensor exhibited good linearity towards glucose with LOD value of 43.200 µmol L<sup>−1</sup>, which proved that the Co(OH)<sub>2</sub>-fCNTs composite is judicious for constructing cost effective and feasible sensor for glucose detection. |
| format | Article |
| id | doaj-art-18b671b81dda4d8887e0011e9b95718b |
| institution | DOAJ |
| issn | 1424-8220 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj-art-18b671b81dda4d8887e0011e9b95718b2025-08-20T02:50:41ZengMDPI AGSensors1424-82202024-12-012423770710.3390/s24237707Evaluation of a Non-Enzymatic Electrochemical Sensor Based on Co(OH)<sub>2</sub>-Functionalized Carbon Nanotubes for Glucose DetectionDiego Bolaños-Mendez0Lenys Fernández1Rafael Uribe2Alisson Cunalata-Castro3Gema González4Isamara Rojas5Andrés Chico-Proano6Alexis Debut7Luis Alberto Celi8Patricio Espinoza-Montero9Escuela de Ciencias Químicas, Pontificia Universidad Católica del Ecuador, Quito 170525, EcuadorEscuela de Ciencias Químicas, Pontificia Universidad Católica del Ecuador, Quito 170525, EcuadorDepartamento de Ingeniería Química, Escuela Politécnica Nacional, Quito 170525, EcuadorEscuela de Ciencias Químicas, Pontificia Universidad Católica del Ecuador, Quito 170525, EcuadorEscuela de Ciencias Físicas y Nanotecnología, Universidad Yachay Tech, Urcuqui 100650, EcuadorDepartamento de Ingeniería Química, Escuela Politécnica Nacional, Quito 170525, EcuadorDepartamento de Ingeniería Química, Escuela Politécnica Nacional, Quito 170525, EcuadorCentro de Nanociencia y Nanotecnología, Universidad de las Fuerzas Armadas ESPE, Sangolqui 170501, EcuadorDepartamento de Ingeniería Química, Escuela Politécnica Nacional, Quito 170525, EcuadorEscuela de Ciencias Químicas, Pontificia Universidad Católica del Ecuador, Quito 170525, EcuadorThis work reports on the assessment of a non-hydrolytic electrochemical sensor for glucose sensing that is developed using functionalized carbon nanotubes (fCNTs)/Co(OH)<sub>2</sub>. The morphology of the nanocomposite was investigated by scanning electron microscopy, which revealed that the CNTs interacted with Co(OH)<sub>2</sub>. This content formed a nanocomposite that improved the electrochemical characterizations of the electrode, including the electrochemical active surface area and capacitance, thus improving sensitivity to glucose. In the electrochemical characterization by cyclic voltammetry and chronoamperometry, the increase in catalytic activity by Co(OH)<sub>2</sub> improved the stability and reproducibility of the glucose sensor without the use of enzymes, and its concentration range was between 50 and 700 μmol L<sup>−1</sup>. The sensor exhibited good linearity towards glucose with LOD value of 43.200 µmol L<sup>−1</sup>, which proved that the Co(OH)<sub>2</sub>-fCNTs composite is judicious for constructing cost effective and feasible sensor for glucose detection.https://www.mdpi.com/1424-8220/24/23/7707carbon nanotubescobalt hydroxideglucoseelectrochemical sensorsnon-enzymatic |
| spellingShingle | Diego Bolaños-Mendez Lenys Fernández Rafael Uribe Alisson Cunalata-Castro Gema González Isamara Rojas Andrés Chico-Proano Alexis Debut Luis Alberto Celi Patricio Espinoza-Montero Evaluation of a Non-Enzymatic Electrochemical Sensor Based on Co(OH)<sub>2</sub>-Functionalized Carbon Nanotubes for Glucose Detection Sensors carbon nanotubes cobalt hydroxide glucose electrochemical sensors non-enzymatic |
| title | Evaluation of a Non-Enzymatic Electrochemical Sensor Based on Co(OH)<sub>2</sub>-Functionalized Carbon Nanotubes for Glucose Detection |
| title_full | Evaluation of a Non-Enzymatic Electrochemical Sensor Based on Co(OH)<sub>2</sub>-Functionalized Carbon Nanotubes for Glucose Detection |
| title_fullStr | Evaluation of a Non-Enzymatic Electrochemical Sensor Based on Co(OH)<sub>2</sub>-Functionalized Carbon Nanotubes for Glucose Detection |
| title_full_unstemmed | Evaluation of a Non-Enzymatic Electrochemical Sensor Based on Co(OH)<sub>2</sub>-Functionalized Carbon Nanotubes for Glucose Detection |
| title_short | Evaluation of a Non-Enzymatic Electrochemical Sensor Based on Co(OH)<sub>2</sub>-Functionalized Carbon Nanotubes for Glucose Detection |
| title_sort | evaluation of a non enzymatic electrochemical sensor based on co oh sub 2 sub functionalized carbon nanotubes for glucose detection |
| topic | carbon nanotubes cobalt hydroxide glucose electrochemical sensors non-enzymatic |
| url | https://www.mdpi.com/1424-8220/24/23/7707 |
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