Serum levels of total IgE and soluble CD23 in bronchial asthma
The aim of the present study was to compare, during the pollen season, serum levels of total IgE and soluble CD23 (sCD23) from patients with allergic bronchial asthma, with those from healthy subjects. Significantly higher levels of total IgE and sCD23 were found in patients with asthma compared to...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
1996-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/S0962935196000075 |
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| _version_ | 1849309278960091136 |
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| author | G. Di Lorenzo P. Mansueto M. Melluso G. Morici D. Cigna G. Candore C. Caruso |
| author_facet | G. Di Lorenzo P. Mansueto M. Melluso G. Morici D. Cigna G. Candore C. Caruso |
| author_sort | G. Di Lorenzo |
| collection | DOAJ |
| description | The aim of the present study was to compare, during the pollen season, serum levels of total IgE and soluble CD23 (sCD23) from patients with allergic bronchial asthma, with those from healthy subjects. Significantly higher levels of total IgE and sCD23 were found in patients with asthma compared to the control group. Both in normal controls and in asthmatic patients, a significant correlation was shown between the levels of these two molecules. In asthmatic patients, significant correlations were found for both total IgE and sCD23, with lung function measured as bronchial responsiveness to inhaled methacholine. These results suggest that in asthmatic patients, in addition to the study of total serum IgE levels, the assessment of sCD23 serum levels may be helpful in the evaluation of disease activity. |
| format | Article |
| id | doaj-art-18b40cb9ea2949f9b765d09fd00a6262 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 1996-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-18b40cb9ea2949f9b765d09fd00a62622025-08-20T03:54:12ZengWileyMediators of Inflammation0962-93511466-18611996-01-0151434610.1155/S0962935196000075Serum levels of total IgE and soluble CD23 in bronchial asthmaG. Di Lorenzo0P. Mansueto1M. Melluso2G. Morici3D. Cigna4G. Candore5C. Caruso6Istituto di Medicina Interna e Geriatria, Università di Palermo, via del Vespro 141, Palermo 90127, ItalyIstituto di Medicina Interna e Geriatria, Università di Palermo, via del Vespro 141, Palermo 90127, ItalyIstituto di Medicina Interna e Geriatria, Università di Palermo, via del Vespro 141, Palermo 90127, ItalyIstituto di Medicina Interna e Geriatria, Università di Palermo, via del Vespro 141, Palermo 90127, ItalyIstituto di Patologia Generale, Università di Palermo, Corse Tukory 211, Palermo 90134, ItalyIstituto di Patologia Generale, Università di Palermo, Corse Tukory 211, Palermo 90134, ItalyIstituto di Patologia Generale, Università di Palermo, Corse Tukory 211, Palermo 90134, ItalyThe aim of the present study was to compare, during the pollen season, serum levels of total IgE and soluble CD23 (sCD23) from patients with allergic bronchial asthma, with those from healthy subjects. Significantly higher levels of total IgE and sCD23 were found in patients with asthma compared to the control group. Both in normal controls and in asthmatic patients, a significant correlation was shown between the levels of these two molecules. In asthmatic patients, significant correlations were found for both total IgE and sCD23, with lung function measured as bronchial responsiveness to inhaled methacholine. These results suggest that in asthmatic patients, in addition to the study of total serum IgE levels, the assessment of sCD23 serum levels may be helpful in the evaluation of disease activity.http://dx.doi.org/10.1155/S0962935196000075 |
| spellingShingle | G. Di Lorenzo P. Mansueto M. Melluso G. Morici D. Cigna G. Candore C. Caruso Serum levels of total IgE and soluble CD23 in bronchial asthma Mediators of Inflammation |
| title | Serum levels of total IgE and soluble CD23 in bronchial asthma |
| title_full | Serum levels of total IgE and soluble CD23 in bronchial asthma |
| title_fullStr | Serum levels of total IgE and soluble CD23 in bronchial asthma |
| title_full_unstemmed | Serum levels of total IgE and soluble CD23 in bronchial asthma |
| title_short | Serum levels of total IgE and soluble CD23 in bronchial asthma |
| title_sort | serum levels of total ige and soluble cd23 in bronchial asthma |
| url | http://dx.doi.org/10.1155/S0962935196000075 |
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