Added value of non-rigid image registration for intrafraction dose accumulation in magnetic resonance imaging-guided prostate radiotherapy

This work investigates potential advantages of non-rigid versus rigid image registration for intrafraction dose reconstruction in hypofractionated prostate radiotherapy. The data of 15 patients were analyzed using 3D cine magnetic resonance imaging (MRI) in combination with machine log files and the...

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Main Authors: Georgios Tsekas, Cornel Zachiu, Gijsbert H. Bol, Johannes C.J. de Boer, Bas W. Raaymakers
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Physics and Imaging in Radiation Oncology
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Online Access:http://www.sciencedirect.com/science/article/pii/S2405631625000168
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author Georgios Tsekas
Cornel Zachiu
Gijsbert H. Bol
Johannes C.J. de Boer
Bas W. Raaymakers
author_facet Georgios Tsekas
Cornel Zachiu
Gijsbert H. Bol
Johannes C.J. de Boer
Bas W. Raaymakers
author_sort Georgios Tsekas
collection DOAJ
description This work investigates potential advantages of non-rigid versus rigid image registration for intrafraction dose reconstruction in hypofractionated prostate radiotherapy. The data of 15 patients were analyzed using 3D cine magnetic resonance imaging (MRI) in combination with machine log files and the accumulated dose distributions were compared to the planned ones. Both image registration methods resulted in comparable results for the majority ( ∼ 95%) of patient fractions. However, better image alignment was reported for the non-rigid method compared to rigid in cases of transient gas pockets, indicating better image registration quality in the presence of large intrafraction deformations.
format Article
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institution Kabale University
issn 2405-6316
language English
publishDate 2025-01-01
publisher Elsevier
record_format Article
series Physics and Imaging in Radiation Oncology
spelling doaj-art-18aa880040b5426d8d5be6657e3643592025-02-12T05:31:21ZengElsevierPhysics and Imaging in Radiation Oncology2405-63162025-01-0133100711Added value of non-rigid image registration for intrafraction dose accumulation in magnetic resonance imaging-guided prostate radiotherapyGeorgios Tsekas0Cornel Zachiu1Gijsbert H. Bol2Johannes C.J. de Boer3Bas W. Raaymakers4Corresponding author.; Department of Radiotherapy, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The NetherlandsDepartment of Radiotherapy, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The NetherlandsDepartment of Radiotherapy, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The NetherlandsDepartment of Radiotherapy, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The NetherlandsDepartment of Radiotherapy, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The NetherlandsThis work investigates potential advantages of non-rigid versus rigid image registration for intrafraction dose reconstruction in hypofractionated prostate radiotherapy. The data of 15 patients were analyzed using 3D cine magnetic resonance imaging (MRI) in combination with machine log files and the accumulated dose distributions were compared to the planned ones. Both image registration methods resulted in comparable results for the majority ( ∼ 95%) of patient fractions. However, better image alignment was reported for the non-rigid method compared to rigid in cases of transient gas pockets, indicating better image registration quality in the presence of large intrafraction deformations.http://www.sciencedirect.com/science/article/pii/S2405631625000168Prostate cancerAdaptive radiotherapyDeformable image registrationRigid image registrationIntrafraction motionHypofractionated radiotherapy
spellingShingle Georgios Tsekas
Cornel Zachiu
Gijsbert H. Bol
Johannes C.J. de Boer
Bas W. Raaymakers
Added value of non-rigid image registration for intrafraction dose accumulation in magnetic resonance imaging-guided prostate radiotherapy
Physics and Imaging in Radiation Oncology
Prostate cancer
Adaptive radiotherapy
Deformable image registration
Rigid image registration
Intrafraction motion
Hypofractionated radiotherapy
title Added value of non-rigid image registration for intrafraction dose accumulation in magnetic resonance imaging-guided prostate radiotherapy
title_full Added value of non-rigid image registration for intrafraction dose accumulation in magnetic resonance imaging-guided prostate radiotherapy
title_fullStr Added value of non-rigid image registration for intrafraction dose accumulation in magnetic resonance imaging-guided prostate radiotherapy
title_full_unstemmed Added value of non-rigid image registration for intrafraction dose accumulation in magnetic resonance imaging-guided prostate radiotherapy
title_short Added value of non-rigid image registration for intrafraction dose accumulation in magnetic resonance imaging-guided prostate radiotherapy
title_sort added value of non rigid image registration for intrafraction dose accumulation in magnetic resonance imaging guided prostate radiotherapy
topic Prostate cancer
Adaptive radiotherapy
Deformable image registration
Rigid image registration
Intrafraction motion
Hypofractionated radiotherapy
url http://www.sciencedirect.com/science/article/pii/S2405631625000168
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