Global Variability of V3 Loop Tetrapeptide Motif: a Concern for HIV-1 Neutralizing Antibodies-based Vaccine Design and Antiretroviral Therapy
Introduction: HIV-1 gp120 V3 GPGR motif has an essential role in viral invasion, cell fusion, and pathogenesis but presents a significant variability that can implicate neutralizing antibodies and antiretroviral drug resistance. Methods: We performed a comprehensive analysis based on 259,288 HIV-...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Pasteur Institute of Iran
2021-10-01
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| Series: | Journal of Medical Microbiology and Infectious Diseases |
| Subjects: | |
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