Single-cell analysis reveals transcriptomic features and therapeutic targets in primary pulmonary lymphoepithelioma-like carcinoma

Single-cell analysis reveals transcriptomic features and therapeutic targets in primary pulmonary lymphoepithelioma-like carcinoma

Abstract Primary pulmonary lymphoepithelioma-like carcinoma (PPLELC) is a rare subtype of non-small-cell lung cancer. Duo to the current lack of precise targeted therapies, there is an urgent need to identify novel therapeutic targets. In this study, we perform single-nucleus transcriptome analysis...

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Main Authors: Binghua Tan, Ke Xu, Yingcheng Lyu, Yicheng Liang, Ruihao Liang, Kai Lei, Jialu Liang, Jing Huang, Kefeng Wang, Duoguang Wu, Wenjian Wang, Xueting Hu, Kexi Wang, Minghui Wang, Huayue Lin
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07819-0
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