Effect of Hydroalcoholic Extract of Cydonia oblonga Miller (Quince) on Sexual Behaviour of Wistar Rats

Cydonia oblonga Miller (quince) is regarded as a potent libido invigorator in Tib-e-Nabvi and Unani System of Medicine. This study was carried out to evaluate the aphrodisiac activity of the hydroalcoholic extract of the fruits of Cydonia oblonga Miller (quince) in Wistar rats. The extract was admin...

Full description

Saved in:
Bibliographic Details
Main Authors: Muhammad Aslam, Ali Akbar Sial
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Advances in Pharmacological Sciences
Online Access:http://dx.doi.org/10.1155/2014/282698
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832564804931289088
author Muhammad Aslam
Ali Akbar Sial
author_facet Muhammad Aslam
Ali Akbar Sial
author_sort Muhammad Aslam
collection DOAJ
description Cydonia oblonga Miller (quince) is regarded as a potent libido invigorator in Tib-e-Nabvi and Unani System of Medicine. This study was carried out to evaluate the aphrodisiac activity of the hydroalcoholic extract of the fruits of Cydonia oblonga Miller (quince) in Wistar rats. The extract was administered orally by gavage in the dose of 500 mg/kg and 800 mg/kg body weight per day as a single dose for 28 days. The observed parameters were mounting frequency, assessment of mating performance, and orientation activities towards females, towards the environment, and towards self. The results showed that after administration of the extract mounting frequency and the mating performance of the rats increased highly significantly P<0.01. The extract also influenced the behaviour of treated animals in comparison to nontreated rats in a remarkable manner, making them more attracted to females. These effects were observed in sexually active male Wistar rats.
format Article
id doaj-art-18a24f48336a44c8af32d34b4b2ea9ff
institution Kabale University
issn 1687-6334
1687-6342
language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Advances in Pharmacological Sciences
spelling doaj-art-18a24f48336a44c8af32d34b4b2ea9ff2025-02-03T01:10:03ZengWileyAdvances in Pharmacological Sciences1687-63341687-63422014-01-01201410.1155/2014/282698282698Effect of Hydroalcoholic Extract of Cydonia oblonga Miller (Quince) on Sexual Behaviour of Wistar RatsMuhammad Aslam0Ali Akbar Sial1Department of Basic Medical Sciences, Faculty of Pharmacy, Ziauddin University, Karachi 75600, PakistanDepartment of Pharmaceutics, Faculty of Pharmacy, Ziauddin University, Karachi 75600, PakistanCydonia oblonga Miller (quince) is regarded as a potent libido invigorator in Tib-e-Nabvi and Unani System of Medicine. This study was carried out to evaluate the aphrodisiac activity of the hydroalcoholic extract of the fruits of Cydonia oblonga Miller (quince) in Wistar rats. The extract was administered orally by gavage in the dose of 500 mg/kg and 800 mg/kg body weight per day as a single dose for 28 days. The observed parameters were mounting frequency, assessment of mating performance, and orientation activities towards females, towards the environment, and towards self. The results showed that after administration of the extract mounting frequency and the mating performance of the rats increased highly significantly P<0.01. The extract also influenced the behaviour of treated animals in comparison to nontreated rats in a remarkable manner, making them more attracted to females. These effects were observed in sexually active male Wistar rats.http://dx.doi.org/10.1155/2014/282698
spellingShingle Muhammad Aslam
Ali Akbar Sial
Effect of Hydroalcoholic Extract of Cydonia oblonga Miller (Quince) on Sexual Behaviour of Wistar Rats
Advances in Pharmacological Sciences
title Effect of Hydroalcoholic Extract of Cydonia oblonga Miller (Quince) on Sexual Behaviour of Wistar Rats
title_full Effect of Hydroalcoholic Extract of Cydonia oblonga Miller (Quince) on Sexual Behaviour of Wistar Rats
title_fullStr Effect of Hydroalcoholic Extract of Cydonia oblonga Miller (Quince) on Sexual Behaviour of Wistar Rats
title_full_unstemmed Effect of Hydroalcoholic Extract of Cydonia oblonga Miller (Quince) on Sexual Behaviour of Wistar Rats
title_short Effect of Hydroalcoholic Extract of Cydonia oblonga Miller (Quince) on Sexual Behaviour of Wistar Rats
title_sort effect of hydroalcoholic extract of cydonia oblonga miller quince on sexual behaviour of wistar rats
url http://dx.doi.org/10.1155/2014/282698
work_keys_str_mv AT muhammadaslam effectofhydroalcoholicextractofcydoniaoblongamillerquinceonsexualbehaviourofwistarrats
AT aliakbarsial effectofhydroalcoholicextractofcydoniaoblongamillerquinceonsexualbehaviourofwistarrats