Smoking and Elevated Preneoadjuvant Chemoradiotherapy Serum Carcinoembryonic Antigen Levels Are Associated With High Tumor Regression Grade and Poor Survival in Patients With Locally Advanced Rectal Cancer

Smoking and Elevated Preneoadjuvant Chemoradiotherapy Serum Carcinoembryonic Antigen Levels Are Associated With High Tumor Regression Grade and Poor Survival in Patients With Locally Advanced Rectal Cancer

ABSTRACT Neoadjuvant chemoradiotherapy (NACRT) is the standard treatment for patients with locally advanced rectal cancer (LARC). Tumor regression grade (TRG) is an essential prognostic factor in determining treatment efficacy. However, the potential factors influencing TRG in patients with rectal c...

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Main Authors: Jen‐Pin Chuang, Hsiang‐Lin Tsai, Po‐Jung Chen, Ching‐Wen Huang, Wei‐Chih Su, Tsung‐Kun Chang, Yen‐Cheng Chen, Ching‐Chun Li, Yung‐Sung Yeh, Jaw‐Yuan Wang
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
carcinoembryonic antigen
neoadjuvant chemoradiotherapy
rectal cancer
smoking
tumor regression grade
Online Access:https://doi.org/10.1002/kjm2.70008
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