Prediabetes and type 2 diabetes but not obesity are associated with alterations in bile acid related gut microbe-microbe and gut microbe-host community metabolism

Prediabetes and type 2 diabetes but not obesity are associated with alterations in bile acid related gut microbe-microbe and gut microbe-host community metabolism

The interplay between bile acids (BAs) and metabolic diseases has gained importance in recent years, with a variety of studies investigating their relationship with diverging results. Therefore, in the present study we performed a detailed analysis of BA metabolism in 492 subjects with different met...

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Main Authors: Kristina Schlicht, Lea Pape, Nathalie Rohmann, Carina Knappe, Johannes Epe, Corinna Geisler, Daniela Pohlschneider, Susanne Brodesser, Lucy Kruse, Maria-Elisabeth Rohlfing, Katharina Hartmann, Kathrin Türk, Jens Marquardt, Jan Beckmann, Witigo von Schönfels, Alexia Beckmann, Perdita Wietzke-Braun, Dominik M. Schulte, Tim Hollstein, Tobias Demetrowitsch, Julia Jensen-Kroll, Fynn Brix, Stefan Schreiber, Andre Franke, Karin Schwarz, Silvio Waschina, Matthias Laudes
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Gut Microbes
Subjects:
Bile acids
type 2 diabetes
gut microbiome
gut community metabolism
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2025.2474143
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