Prevalence and factors associated with vaccine hesitancy for the booster dose of COVID-19 among undergraduate medical students in Puducherry: a cross-sectional study

Background & Aims: COVID-19, caused by SARS-CoV-2, has severely impacted global public health and economies, including India. Vaccination remains the primary preventive measure against the pandemic. Despite its importance, vaccine hesitancy remains a significant barrier, even among healthcare wo...

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Main Authors: Srimadhi Muthaiyan, Rajsri Thuthikadu Rajasekaran, Bhuvaneswari Natarajan
Format: Article
Language:English
Published: Urmia University of Medical Sciences 2025-01-01
Series:Journal of Research in Applied and Basic Medical Sciences
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Online Access:http://ijrabms.umsu.ac.ir/article-1-358-en.pdf
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author Srimadhi Muthaiyan
Rajsri Thuthikadu Rajasekaran
Bhuvaneswari Natarajan
author_facet Srimadhi Muthaiyan
Rajsri Thuthikadu Rajasekaran
Bhuvaneswari Natarajan
author_sort Srimadhi Muthaiyan
collection DOAJ
description Background & Aims: COVID-19, caused by SARS-CoV-2, has severely impacted global public health and economies, including India. Vaccination remains the primary preventive measure against the pandemic. Despite its importance, vaccine hesitancy remains a significant barrier, even among healthcare workers (HCWs). This study aimed to estimate the prevalence and identify factors associated with vaccine hesitancy for the COVID-19 booster dose among undergraduate medical students in Puducherry.   Materials & Methods: A cross-sectional study was conducted from April to June 2022 among undergraduate medical students in Puducherry. A sample of 476 participants was selected using simple random sampling. Data were collected through an online semi-structured questionnaire based on the WHO SAGE tool, which included socio-demographic details, vaccination history, and perceptions about COVID-19 and vaccination. Statistical analysis was performed using SPSS version 23. Bivariate analysis (Chi-square test) was conducted to assess associations between socio-demographic factors and vaccine hesitancy. Results: Among the 476 participants, 13.03% were classified as vaccine-hesitant (score < 30). Significant associations were found between vaccine hesitancy and age (p = 0.027), year of study (p = 0.002), religion (p = 0.010), and the presence of comorbidities (p = 0.005). Hesitancy was higher among participants under 20 years of age, in their 4th year of study, and among Christians. Personal or community negative experiences with vaccination, fear of injection pricks, and perceived lack of scientific evidence were major reasons for hesitancy. Conclusion: Vaccine hesitancy for the COVID-19 booster dose among undergraduate medical students is influenced by multiple socio-demographic, experiential, and perceptual factors. Addressing these factors through targeted education, engagement with religious leaders, clear communication about vaccine safety and benefits, and supportive interventions at vaccination sites is crucial. These strategies could enhance vaccine uptake and contribute to controlling the pandemic. Further research should explore vaccine hesitancy in diverse populations and evaluate the effectiveness of these interventions.
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spelling doaj-art-18988171309447068d4e0bcb99554fa22025-08-20T01:47:29ZengUrmia University of Medical SciencesJournal of Research in Applied and Basic Medical Sciences2717-00982025-01-0111198106Prevalence and factors associated with vaccine hesitancy for the booster dose of COVID-19 among undergraduate medical students in Puducherry: a cross-sectional studySrimadhi Muthaiyan0Rajsri Thuthikadu Rajasekaran1Bhuvaneswari Natarajan2 Assistant Professor, Department of Community Medicine, Faculty of Medicine, Sri Lalithambigai Medical College and Hospital, Dr. MGR Educational and Research Institute, Chennai Assistant Professor, Department of Community Medicine, Faculty of Medicine, Sri Lalithambigai Medical College and Hospital, Dr. MGR Educational and Research Institute, Chennai sssistant Professor, Department of Community Medicine, ESIC Medical College and Hospital, KK Nagar, Chennai Background & Aims: COVID-19, caused by SARS-CoV-2, has severely impacted global public health and economies, including India. Vaccination remains the primary preventive measure against the pandemic. Despite its importance, vaccine hesitancy remains a significant barrier, even among healthcare workers (HCWs). This study aimed to estimate the prevalence and identify factors associated with vaccine hesitancy for the COVID-19 booster dose among undergraduate medical students in Puducherry.   Materials & Methods: A cross-sectional study was conducted from April to June 2022 among undergraduate medical students in Puducherry. A sample of 476 participants was selected using simple random sampling. Data were collected through an online semi-structured questionnaire based on the WHO SAGE tool, which included socio-demographic details, vaccination history, and perceptions about COVID-19 and vaccination. Statistical analysis was performed using SPSS version 23. Bivariate analysis (Chi-square test) was conducted to assess associations between socio-demographic factors and vaccine hesitancy. Results: Among the 476 participants, 13.03% were classified as vaccine-hesitant (score < 30). Significant associations were found between vaccine hesitancy and age (p = 0.027), year of study (p = 0.002), religion (p = 0.010), and the presence of comorbidities (p = 0.005). Hesitancy was higher among participants under 20 years of age, in their 4th year of study, and among Christians. Personal or community negative experiences with vaccination, fear of injection pricks, and perceived lack of scientific evidence were major reasons for hesitancy. Conclusion: Vaccine hesitancy for the COVID-19 booster dose among undergraduate medical students is influenced by multiple socio-demographic, experiential, and perceptual factors. Addressing these factors through targeted education, engagement with religious leaders, clear communication about vaccine safety and benefits, and supportive interventions at vaccination sites is crucial. These strategies could enhance vaccine uptake and contribute to controlling the pandemic. Further research should explore vaccine hesitancy in diverse populations and evaluate the effectiveness of these interventions.http://ijrabms.umsu.ac.ir/article-1-358-en.pdfbooster dosecovid-19vaccine hesitancywho sage tool
spellingShingle Srimadhi Muthaiyan
Rajsri Thuthikadu Rajasekaran
Bhuvaneswari Natarajan
Prevalence and factors associated with vaccine hesitancy for the booster dose of COVID-19 among undergraduate medical students in Puducherry: a cross-sectional study
Journal of Research in Applied and Basic Medical Sciences
booster dose
covid-19
vaccine hesitancy
who sage tool
title Prevalence and factors associated with vaccine hesitancy for the booster dose of COVID-19 among undergraduate medical students in Puducherry: a cross-sectional study
title_full Prevalence and factors associated with vaccine hesitancy for the booster dose of COVID-19 among undergraduate medical students in Puducherry: a cross-sectional study
title_fullStr Prevalence and factors associated with vaccine hesitancy for the booster dose of COVID-19 among undergraduate medical students in Puducherry: a cross-sectional study
title_full_unstemmed Prevalence and factors associated with vaccine hesitancy for the booster dose of COVID-19 among undergraduate medical students in Puducherry: a cross-sectional study
title_short Prevalence and factors associated with vaccine hesitancy for the booster dose of COVID-19 among undergraduate medical students in Puducherry: a cross-sectional study
title_sort prevalence and factors associated with vaccine hesitancy for the booster dose of covid 19 among undergraduate medical students in puducherry a cross sectional study
topic booster dose
covid-19
vaccine hesitancy
who sage tool
url http://ijrabms.umsu.ac.ir/article-1-358-en.pdf
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