Cytokine profiling reveals HLA-linked Th2 and Th17 driven immune activation in pemphigus vulgaris patients and genetically susceptible healthy controls

Cytokine profiling reveals HLA-linked Th2 and Th17 driven immune activation in pemphigus vulgaris patients and genetically susceptible healthy controls

IntroductionCytokines and chemokines direct the inflammatory response and may serve as markers of immune dysregulation in Pemphigus vulgaris (PV), an autoimmune blistering skin disorder. Previous studies on limited numbers of patients and cytokine profiles in PV have produced equivocal results regar...

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Bibliographic Details
Main Authors: Rebekah R. Schwartz, Kristina Seiffert-Sinha, Animesh A. Sinha
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Immunology
Subjects:
Pemphigus
HLA
cytokine
autoimmunity
Th17
Th2
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1500231/full
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