The heterogeneity of NOTCH1 to tumor immune infiltration in pan-cancer

The heterogeneity of NOTCH1 to tumor immune infiltration in pan-cancer

Abstract NOTCH1 signaling, a vital regulator of cell proliferation and differentiation, is widely involved in the occurrence and development of malignant tumors. Pharmacological regulation of NOTCH1 is promising in tumor immunotherapy, whereas the effective rate of existing therapies remains low. NO...

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Bibliographic Details
Main Authors: XiaoJun Duan, Rihan Wu, Mingyang Zhang, Kexin Li, Lei Yu, Huirong Sun, Xingxia Hao, Changshan Wang
Format: Article
Language:English
Published: Nature Portfolio 2024-11-01
Series:Scientific Reports
Subjects:
NOTCH1
Tumor heterogeneity
Immune infiltration
Angiogenesis
tsRNA
Online Access:https://doi.org/10.1038/s41598-024-79883-1
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