Association of the nutritional risk index recorded prior to allogeneic hematopoietic cell transplantation with the clinical prognosis in children
Abstract Introduction The nutritional risk index (NRI), calculated using serum albumin levels and body weight ratio is a known prognostic factor in adult hematopoietic cell transplantation (HCT). However, its usefulness in pediatric HCT settings remains unclear. Methods In a retrospective study, we...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-02-01
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| Series: | eJHaem |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/jha2.1054 |
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| Summary: | Abstract Introduction The nutritional risk index (NRI), calculated using serum albumin levels and body weight ratio is a known prognostic factor in adult hematopoietic cell transplantation (HCT). However, its usefulness in pediatric HCT settings remains unclear. Methods In a retrospective study, we examined pre‐transplant NRI impact on outcomes in 82 pediatric patients undergoing allogeneic HCT. Results The 2‐year non‐relapse mortality (NRM) rate was 7.94% (95% confidence interval [CI], 3.05%–19.8%) and 30.8% (95% CI, 16.7%–52.2%) in the high and low NRI groups, respectively (p = 0.0037). Conclusion We found that poor nutritional status prior to pediatric HCT led to a worse prognosis, including increased NRM. |
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| ISSN: | 2688-6146 |