Dynamic analysis of stochastic transcription cycles.

In individual mammalian cells the expression of some genes such as prolactin is highly variable over time and has been suggested to occur in stochastic pulses. To investigate the origins of this behavior and to understand its functional relevance, we quantitatively analyzed this variability using ne...

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Bibliographic Details
Main Authors: Claire V Harper, Bärbel Finkenstädt, Dan J Woodcock, Sönke Friedrichsen, Sabrina Semprini, Louise Ashall, David G Spiller, John J Mullins, David A Rand, Julian R E Davis, Michael R H White
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1000607&type=printable
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